A recent analysis reveals that treatment of male breast cancer has evolved over the years. In addition, certain patient-, tumor-, and treatment-related factors are linked with better survival.
Read moreLike entrance and exit doors on a building, a cell's outer surface has doors — channels, pumps, and transporters that selectively control what molecules enter or exit. In the immune system, T cells possess unique sets of 'doors', including ones that specialize in calcium ion movement. Now, researchers describe a unique mechanism for coordinating these calcium entrance and exit 'doors' on T cells that helps them carry out their jobs and ensure normal immune function.
Read moreA new study examines shifts in fertility behaviors among Generation X women in the United States — those born between 1965-1982 — compared to their Baby Boomer counterparts, and explores whether the fertility of college-educated women is increasing more quickly across cohorts in Generation X than the fertility of their less educated counterparts.
Read moreBreast cancer is one of the most prevalent cancers, and some forms rank among the most difficult to treat. Its various types and involvement of many different cells makes targeting such tumors difficult. Now, researchers have used a state-of-the-art technology to profile each cell during normal breast development in order to understand what goes wrong in cancer.
Read moreScientists have revealed how the electrical patterns formed within an embryo initiate a cascade of molecular changes that culminate in the development of cartilage and bone. Prior studies have shown these electrical patterns appear like blueprints of the tissues and organs that eventually take shape as the embryo matures. The new study demonstrates that voltage gated calcium channels 'read' the electrical pattern, setting off the expression of genes that guide differentiation to mature cells.
Read moreResearchers have identified a pair of proteins believed to be critical for spreading, or metastasizing, breast cancer to bone.
Read moreWomen who reach menopause before the age of 50 have an increased risk of cardiovascular disease, according to researchers.
Read moreWhen it comes to repairing injured tissue, specialized cells in the body known as fibroblasts are called into action. Fibroblasts give rise to healing cells called myofibroblasts, which generally is good in the short term — but bad when myofibroblast activation gets out of hand. Now, researchers show how fibroblast activation and myofibroblast formation occurs, providing clues for how to target fibrosis — which impacts several chronic diseases.
Read moreStudy results help clarify how to safely prevent tuberculosis (TB) in women living with HIV who are pregnant or have recently given birth, are taking antiretroviral therapy, and live where TB is highly prevalent.
Read moreA multistakeholder coalition has issued clinical recommendations for the optimal prevention of secondary fracture among people aged 65 years and older with a hip or vertebral fracture — the most serious complication associated with osteoporosis.
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