A new study uncovered new information on why the Ebola virus can exert such catastrophic effects on the infected person. They've described for the first time how the virus disables T cells, an important line of immune defense, thus rendering the infected person less able to combat the infection.
Read moreA single dose of a highly diluted VSV-Ebola virus (EBOV) vaccine — approximately one-millionth of what is in the vaccine being used to help control the ongoing Ebola outbreak in the Democratic Republic of the Congo — remains fully protective against disease in experimentally infected monkeys, according to scientists. The investigators completed the dosage study using cynomolgus macaques and an updated vaccine component to match the EBOV Makona strain that circulated in West Africa from 2014-16.
Read moreScientists have assembled a set of genetic sequences that enable the reference genome to better reflect global genetic diversity. The new sequences improve the utility of the human reference genome, a touchstone resource for modern genetics and genomics research.
Read moreLow-income urban neighborhoods not only have more mosquitoes, but they are larger-bodied, indicating that they could be more efficient at transmitting diseases. So reports investigating how socioeconomics influences mosquito-borne disease risk in Baltimore, Maryland.
Read moreViruses are non-living creatures, consisting of genetic material encased in a protein coat. Once the virus infects a living organism, it can replicate itself and continue on. But what happens if a virus lacks the proper tools to infect an organism? How can it propagate? Researchers have uncovered a novel virus that may help answer those questions.
Read moreBy collaborating globally in a new, large-scale effort, researchers have made strong progress in sequencing genomes from regions and countries across Africa. These findings will enable more broadly representative and relevant studies ranging from basic through clinical genetics.
Read moreResearchers have now turned a CRISPR RNA-cutting enzyme into an antiviral that can be programmed to detect and destroy RNA-based viruses in human cells.
Read moreA computational analysis has identified key regions in the United States where model-based predictions of mosquito species distribution could be improved.
Read moreIn animals, infections are fought by the immune system. Studies on an unusual virus infecting wild koalas, by a team of researchers reveal a new form of "genome immunity."
Read moreScientists show, on the molecular level, how an experimental vaccine offers long-term protection against the disease.
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