Researchers find college football players' weight gain leads to heart problems

Weight gain and high blood pressure in college football players leads to adverse changes in cardiac structure and function, indicating monitoring and early intervention is needed for this young and otherwise healthy athletic population, according to a new study.

Read more

Special cells contribute to regenerate the heart in Zebrafish

It is already known that zebrafish can flexibly regenerate their hearts after injury. An international research group now shows that certain heart muscle cells play a central role in this process. The insights gained could be used to initiate a similar repair process in the human heart.

Read more

Drug treats inflammation associated with genetic heart disease

When young athletes experiences sudden cardiac death as they run down the playing field, it's usually due to arrhythmogenic cardiomyopathy (ACM), an inherited heart disease. Now, researchers have shed new light on the role of the immune system in the progression of ACM and, in the process, discovered a new drug that might help prevent ACM disease symptoms and progression to heart failure in some patients.

Read more

Tissue damage caused by a heart attack to be reduced by 30%?

A heart attack is caused by a clot that blocks the artery blood flow. Under these conditions, the affected tissues undergo a rapid necrosis. But why? Scientists discovered that the synthesis of a lipid provokes the necrosis. This lipid accumulates in the absence of oxygen and blocks cellular functions. By inhibiting its synthesis in a mouse suffering a heart attack, the biologists were able to reduce the tissue damage by 30%.

Read more

Potential drug to treat heart attacks

Administered within hours of an attack, the potential drug would prevent scarring that can lead to heart failure. For the study, the researcher used a drug that targets a key component of the cellular clock mechanism. The medication disrupts expression of genes that trigger adverse immune responses after a heart attack. When mice were given the drug after a heart attack, they were found to have less inflammation and improved cardiac repair.

Read more