Non-pharmacologic treatments may be more effective for psychiatric symptoms of dementia

A systematic review and meta-analysis suggests outdoor activities were more clinically effective than anti-psychotic medication for treating physical aggression in patients with dementia. For patients with physical agitation, massage and touch therapy were more efficacious than usual care or caregiver support.

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Microbleeds may worsen outcome after head injury

Using advanced imaging, researchers have uncovered new information regarding traumatic microbleeds, which appear as small, dark lesions on MRI scans after head injury but are typically too small to be detected on CT scans. The findings published in Brain suggest that traumatic microbleeds are a form of injury to brain blood vessels and may predict worse outcomes. The study was conducted in part by scientists at the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health.

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Dementia spreads via connected brain networks

Scientists used maps of brain connections to predict how brain atrophy would spread in individual patients with frontotemporal dementia (FTD), adding to growing evidence that the loss of brain cells associated with dementia spreads via the synaptic connections between established brain networks.

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Opioid Rx dosages drop with state law changes

The total amount of opioids dispensed per new opioid prescription decreased by 22% in Penn Medicine outpatient practices in New Jersey after the state passed a law limiting prescriptions to a five-day supply for new opioid prescriptions. Penn Medicine implemented an electronic health record (EMR) alert, or 'nudge,' to notify clinicians if that limit had been reached.

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Slower walkers have older brains and bodies at 45

The walking speed of 45-year-olds can be used as a marker of their aging brains and bodies. The evidence was there in neurocognitive testing these individuals took at age 3 to indicate who would become the slower walkers. At 45, slower walkers have 'accelerated aging' on a 19-measure scale devised by researchers, and their lungs, teeth and immune systems tended to be in worse shape than the people who walked faster.

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