Variation in transplant centers' use of less-than-ideal organs

In 2010-2016, many US transplant centers commonly accepted deceased donor kidneys with less desirable characteristics. The use of these organs varied widely across transplant centers, however, and differences were not fully explained by the size of waitlists or the availability of donor organs.

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Health care intervention: Treating high-need, high-cost patients

Patients with complex needs — serious mental and physical health problems and substance use disorders — flock to emergency rooms costing the health care system billions every year. A new study suggests a nontraditional approach to these patients can significantly improve their daily functioning and health outcomes.

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Oxygen in hyperbaric chamber provides relief after radiotherapy

Hyperbaric oxygen therapy (HBOT) can relieve self-reported symptoms and side-effects of radiotherapy against cancer in the pelvic region, a study shows. After 30-40 sessions in a hyperbaric chamber, many patients experienced reductions in bleeding, urinary incontinence, and pain alike.

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Scientists develop test for uncommon brain diseases

Scientists have developed an ultrasensitive new test to detect abnormal forms of the protein tau associated with uncommon types of neurodegenerative diseases called tauopathies. This advance gives them hope of using cerebrospinal fluid, or CSF — an accessible patient sample — to diagnose these and perhaps other, more common neurological diseases, such as Alzheimer's disease.

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Widely available drug reduces head injury deaths

A low cost and widely available drug could reduce deaths in traumatic brain injury patients by as much as 20%, depending on the severity of injury, according to a major study. The researchers say that tranexamic acid (TXA), a drug that prevents bleeding into the brain by inhibiting blood clot breakdown, has the potential to save hundreds of thousands of lives.

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