For the first time, researchers have created mouse blastocyst-like structures, or 'blastoids,' from a single cultured cell. The work could help advance research into development as well as inform issues around pregnancy, infertility, or health problems later in the offspring's life.
Read moreBioscientists develop a method to observe patterns of early embryonic development, during which ectodermal cells diverge toward their fates as skin, organs and the nervous system.
Read moreA research team found muscle cells treated with statins released the amino acid called glutamate at much higher levels than muscle cells that were untreated. As glutamate is a potent activator of muscle pain receptors, this release was proposed to trigger the sensation of muscle pain.
Read moreBioengineers are a step closer to making CAR T-cell therapy safer, more precise and easy to control. They developed a system that allows them to select where and when CAR T cells get turned on so that they destroy cancer cells without harming normal cells. The system requires two 'keys' — the drug Tamoxifen and blue light — to activate CAR T cells to bind to their targets.
Read moreResearchers have discovered that a key cell type involved in liver injury and cancer consists of two cellular families with different origins and functions.
Read moreResearchers showed in animal models that the default injury response of spinal discs can be temporarily stopped to allow for better treatment.
Read moreFood science and human nutrition researchers are interested in the potential of inflammation-fighting compounds found in the silverskin and husk of coffee beans, not only for their benefits in alleviating chronic disease, but also in adding value to would-be 'waste' products from the coffee processing industry.
Read moreFor years, scientists have used cells grown in petri dishes to study the metabolic processes that fuel the immune system. But a new report suggests looking outside the dish and into living organisms gives a drastically different view of the way immune cells process and use energy.
Read moreThe first comprehensive look at the immune system of the fetal gut shows that it is far more developed before birth, and could help develop new maternal vaccines and reveal if we are predisposed to autoimmune diseases before birth.
Read more