Bioprinting: Living cells in a 3D printer

A high-resolution bioprinting process has been developed: Cells can now be embedded in a 3D matrix printed with micrometer precision — at a printing speed of one meter per second, orders of magnitude faster than previously possible. Tissue growth and the behavior of cells can be controlled and investigated particularly well by embedding the cells in a delicate 3D framework. This is achieved using so called 'bioprinting' techniques.

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'Instant liver, just add water'? Not quite, but a better way to grow multiple organs

Pluripotent stem cells can be used to make experimental models of organ systems, but current techniques often produce models that bear limited resemblance to true organs. Researchers developed an improved method to make a sophisticated three-dimensional organoid model of the liver, pancreas, and bile ducts. The model may help researchers understand how these organs form and how genetic mutations can lead to diseases in these organs.

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GAS7 protein allows cells to eat

Phagocytosis can be viewed as a primitive immune system used by all cells. When a pathogen is near the cell, the cell membrane will deform to engulf the pathogen and dispose of it. Researchers have found that a two-dimensional sheet formed by the protein GAS7 is critical for this process, identifying through crystallography and microscopy two key hydrophilic loops in the protein.

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When added to gene therapy, plant-based compound may enable faster, more effective treatments

Today's standard process for administering gene therapy is expensive and time-consuming — a result of the many steps required to deliver the healthy genes into the patients' blood stem cells to correct a genetic problem. Scientists believe they have found a way to sidestep some of the current difficulties, resulting in a more efficient gene delivery method that would save money and improve treatment outcomes.

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