Powerful new genomics method can be used to reveal the causes of rare genetic diseases

The technique makes use of the fact that people inherit two copies or ''alleles'' of virtually every gene, one from the mother and one from the father. The new method compares activity levels of maternal and paternal alleles across the genome and detects when the activity of an allele lies far enough outside the normal range to be a plausible cause of disease.

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Volleyball: The secret to sneaky float serves

A team of researchers performed wind tunnel experiments to determine the role of asymmetry caused by the orientation of a volleyball on its aerodynamic characteristics. They found that switching from the standard panel arrangement to a hexagonal or dimpled pattern may improve the consistency of flight, with many potential applications in aviation.

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Dual approach needed to save sinking cities and bleaching corals

Local conservation can boost the climate resilience of coastal ecosystems, species and cities and buy them time in their fight against sea-level rise, ocean acidification and warming temperatures, a study by scientists suggests. In all but extreme situations, these interventions significantly buffer the impacts of climate change and can buy sinking cities and bleaching corals time to adapt until the beneficial impacts of global emissions reductions kick in.

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Thinner shells for delivering gentler therapeutic bursts

Releasing drugs that are packaged into microcapsules requires a significant amount of force, and the resulting burst can cause damage to human tissues or cause blood clots. A new technique creates lopsided microcapsule 'shells' that can burst and release their cargo at much lower pressure, making them safer for use in the body.

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