In the quest for a more youthful appearance, many people slather ointments on their skin or undergo injections of dermal fillers. But topical treatments often aren't very effective because they don't penetrate deep within the skin, whereas the results from injections typically last for only a few months and can be painful. Now, researchers have developed a needle-free 'exosome' treatment that reduces wrinkles in UV-exposed mice.
Read moreIn the presence of some disruptive elements, cancer cells are unable to replicate its DNA optimally. While known to be linked to the increase in genetic mutations, the exact mechanism at work remained unknown until now. By deciphering how replication stress induces the loss or gain of whole chromosomes in the daughters of cancer cells, researchers provide new knowledge that will ultimately lead to better diagnosis and possibly better treatment of cancer.
Read moreA space-age metal that formed part of the asteroid that destroyed the dinosaurs could provide a new method of treating cancer tumors selectively using light.
Read moreIn experiments with mice, researchers have shown they can harness the power of iNKT cells to attack tumor cells and treat cancer. The new method suppressed the growth of multiple types of human tumors that had been transplanted into the animals.
Read moreActive mutations of a certain signaling receptor protein called KIT tyrosine kinase are found in several cancers, such as acute myeloid leukemia (AML). However, the different locations in the AML cells where KIT induces cancer-specific signaling remain unclear. Now, a group of scientists has aimed to answer this question by using a newly synthesized compound (along with other existing ones) that targets intracellular transport, which may offer an attractive strategy to combat cancer.
Read moreIn a proof-of-concept study, researchers have shown that exosomes harvested from human skin cells are more effective at repairing sun-damaged skin cells in mice than popular retinol or stem cell-based treatments currently in use. Additionally, the nanometer-sized exosomes can be delivered to the target cells via needle-free injections.
Read moreCombining a new class of drug with two other compounds can significantly shrink lung tumors in mice and human cancer cells, new research shows. The study looked at G12C KRAS inhibitors, a new type of drug that targets a specific mutation that can cause cells to multiply uncontrollably and lead to fast-growing cancers.
Read moreA new needle-free flu vaccine patch revved up the immune system much like a traditional flu shot without any negative side effects. The research represents an important step toward a technology that could replace needle-based vaccination methods that are difficult to deploy in developing countries.
Read moreScientists have studied air quality inside of four cannabis growing facilities in Nevada and California. They recorded high levels of BVOCs (biogenic volatile organic compounds) and butane inside each growing facility, which can contribute to the formation of ground-level ozone if released into the outdoors.
Read moreA treatment for psoriasis could be repurposed to treat a rare but aggressive form of youth cancer, new findings suggest.
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