Scientists have carried out one of the most comprehensive studies into how immune cells sense and respond to their environment to fight infection and destroy tumors. The research team said the results provide important insights into how immune responses might be manipulated for the treatment of autoimmune diseases and cancer.
Read moreA new type of drug that blocks one of cancer's key evolutionary escape routes from chemotherapy could be used to treat aggressive breast cancers, a new study has shown.
Read moreA researcher who is currently doing his post-doctoral training at Stanford University, has successfully invented a novel transfection method to deliver DNA into immune cells with minimal stress on these cells. This new technique is expected to boost DNA-based cancer immunotherapy by significantly improving the process of generating high-quality genetically modified immune cells.
Read moreWound inflammation which results in impaired wound healing can have serious consequences for patients. Researchers have discovered a new defensive mechanism which enables our skin to actively kill bacteria. Central to this mechanism is a cellular messenger molecule known as 'interleukin 6', whose mode of action may be used in the future to prevent wound infections.
Read moreA novel anticancer molecule created by researchers showed therapeutic activity in preclinical models of various cancer types.
Read moreTwo new studies report progress in using stem cells to develop new therapies for Pelizaeus-Merzbacher disease (PMD), a rare genetic condition affecting boys that can be fatal before 10 years of age.
Read moreHead and neck melanoma among pediatric, adolescent and young adult populations in the United States and Canada increased by 51.1% from 1995 to 2014.
Read moreA research team has discovered a metabolic vulnerability in multiple types of cancer cells that bear a common genetic mutation affecting cellular machines called spliceosomes.
Read moreInvestigators analyzed 40 years of cancer burden data and examined patterns of incidence and mortality for various cancers, finding examples for which incidence and mortality moved in concert and examples where discordance in incidence and mortality indicate that overdiagnosis may be at play.
Read moreScientists have found a common, new source of tumor mutations that could offer three levels of therapy with a cancer vaccine: 1) a broadly protective, or pan-cancer vaccine 2) cancer-type specific vaccines (e.g. breast vs. pancreatic), 3) personalized cancer vaccines based on mutations unique to an individual.
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