Schizophrenia – PossibleThreat Articles

Schizophrenia risk gene linked to cognitive deficits in mice

October 24, 2019 0 Comments Disorders and Syndromes, Gene Therapy, Genes, Memory, Mental Health, Mental Health Research, Personalized Medicine, Schizophrenia

Researchers have discovered in mice how one of the few genes definitively linked to schizophrenia, called SETD1A, likely confers risk for the illness. Mice genetically engineered to lack a functioning version of the enzyme-coding gene showed abnormalities in working memory, mimicking those commonly seen in patients. Restoring the gene's function corrected the working memory deficit and counteracting its deficiency also repaired neuronal circuit deficits in adult mice — suggesting clues for potential treatment strategies.

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Society is rejecting facts; medical researchers can help

October 16, 2019 0 Comments Depression, Educational Policy, Health Policy, K-12 Education, Medical Education and Training, Public Health Education, Schizophrenia, Scientific Conduct, STEM Education

Anecdotes, fake news and social media have created a skeptical and misinformed public who is rejecting the facts. A commentary says that medical researchers must help the public understand the rigorous process of science and help them to discern an anecdote from peer-reviewed scientific results. The best way to do this? By continuing to ensure integrity, rigor, reproducibility and replication of their science and to earn the public's trust by being morally responsible and completely free of any influences.

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New insights into biological underpinnings of schizophrenia

October 16, 2019 0 Comments Disorders and Syndromes, Genes, Human Biology, Mental Health, Mental Health Research, Personalized Medicine, Psychiatry, Schizophrenia

Researchers have implicated 10 new genes in the development of schizophrenia using a method called whole exome sequencing, the analysis of the portion of DNA that codes for proteins. A global consortium of schizophrenia research teams incorporated genetic data from over 125,000 people to gain deeper insights into the genetic underpinnings of schizophrenia.

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Nervous system's role in age-related weakness

October 10, 2019 0 Comments Fitness, Healthy Aging, Medical Topics, Neuropathy, neuroscience, Schizophrenia, Steroids, Stress

A study finds new evidence to support the belief that the nervous system plays an important role in age-related weakness.

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Uncovering the presynaptic distribution and profile of mitochondria

October 10, 2019 0 Comments Amyotrophic Lateral Sclerosis, Child Development, Human Biology, Intelligence, Nervous System, neuroscience, Personalized Medicine, Schizophrenia

Scientists have provided unprecedented insight into the presynaptic distribution and profile of mitochondria in the developing and mature calyx of Held.

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Core symptom of schizophrenia reversed in adult mice

October 10, 2019 0 Comments Animal Learning and Intelligence, Biotechnology and Bioengineering, Brain Tumor, Disorders and Syndromes, Memory, Mental Health Research, mice, Nervous System, Schizophrenia

Researchers have restored normal working memory to a mouse model of schizophrenia, eliminating a core symptom of the disorder that, in people, has proven virtually impossible to treat.

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The propensity to hear 'voices' in Schizophrenia may be established by infancy

October 2, 2019 0 Comments Disorders and Syndromes, Mental Health, Mental Health Research, Patient Education and Counseling, Perception, Psychology Research, Schizophrenia, Today's Healthcare

Findings reveal how auditory hallucinations may arise in patients with schizophrenia and provide potential new targets for early detection and treatment.

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Sustainable development goals only achievable through cross-disciplinary research

September 24, 2019 0 Comments Addiction, Alcoholism, Alzheimer's, Child Development, Multiple Sclerosis, Schizophrenia, Social Psychology

It is not possible to achieve the sustainable development goals (SDG) if science does not contribute with cross-disciplinary knowledge and understanding of how systems are interconnected.

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New target regulating mitochondria during stress

September 19, 2019 0 Comments Anxiety, Disorders and Syndromes, Heart Disease, Osteoporosis, Schizophrenia, Stroke, Stroke Prevention, Women's Health

Like an emergency response team that is called into action to save lives, stress response proteins in the heart are activated during a heart attack to help prevent cell death. As part of this process, researchers show for the first time that one of these specialized emergency responder proteins, known as MCUB, temporarily decreases harmful levels of calcium transport into mitochondria, the energy-generating batteries of cells.

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More operations are scheduled if doctor is well rested

September 18, 2019 0 Comments Consumer Behavior, Disorders and Syndromes, Medical Education and Training, Multiple Sclerosis, Patient Education and Counseling, Schizophrenia, Today's Healthcare, Wounds and Healing

Researchers have investigated how orthopedic surgeons make decisions regarding surgery, and how the decisions are related to how much of their work shift they have completed. The results show that a patient who meets the surgeon at the end of his or her shift is less likely to be scheduled for surgery.