Insulin-like growth factor 1 (IGF1) is essential for allowing tendons to adapt to physical activity and grow properly, according to basic science research. The findings provide a strong rationale for pursuing clinical trials to explore IGF1 as a new target for treating tendon injuries in humans.
Read morePTEN, a tumor suppressor gene mutated in about 20% of prostate cancers, relies on another gene, ARID4B, to function.
Read moreIn experiments with mice, researchers have shown they can harness the power of iNKT cells to attack tumor cells and treat cancer. The new method suppressed the growth of multiple types of human tumors that had been transplanted into the animals.
Read moreThe VITamin D and OmegA-3 Trial (VITAL) is the largest and most recent to test whether vitamin D or fish oil can effectively prevent cancer or cardiovascular disease. Results to date have been mixed but show promise for some outcomes, now confirmed by updated pooled (meta) analyses.
Read moreResearchers have described the role of mitochondrial fission factor (MFF) in controlling survival of cancer cells, suggesting the protein could represent a promising therapeutic target.
Read moreResearchers have discovered that some cancer cells survive chemotherapy by eating their neighboring tumor cells. The study suggests that this act of cannibalism provides these cancer cells with the energy they need to stay alive and initiate tumor relapse after the course of treatment is completed.
Read moreDuchenne muscular dystrophy (DMD) is a rare but devastating genetic disorder that causes muscle loss and physical impairments. Researchers have shown in a mouse study that the powerful gene editing technique known as CRISPR may provide the means for lifelong correction of the genetic mutation responsible for the disorder.
Read moreResearchers have developed a new anti-cancer nanomedicine for targeted cancer chemotherapy. This new nano-tool provides a new approach to use cell-based nanomedicines for efficient cancer chemotherapy.
Read moreSelective mammography screening can provide potentially lifesaving early detection of breast cancer in men who are at high risk for the disease, according to a new landmark study.
Read moreA drug used to treat enlarged prostate may also slow the progression of Parkinson's disease, according to a new study.
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