Why targeted immuno-oncology drugs sometimes fail
Researchers report a discovery that helps scientists understand why some tumors lack immune cell infiltration and are therefore unresponsive to newer PD-1 targeted therapies.
Read moreProstate Cancer
Clues to improve cancer immunotherapy revealed
A new study indicates a way for cancer immunotherapy to spur a more robust immune response. Such knowledge could lead to the development of better cancer vaccines and more effective immunotherapy drugs called checkpoint inhibitors.
Read moreA marine pathogenic bacterium forms specialized cells for dissemination
Vibrio parahaemolyticus can be found in the tidal zones in estuarine areas. The marine bacterium causes acute gastroenteritis in humans and is the leading cause for seafood borne illnesses in the world. Researchers have now identified specialized "adventurer" cells that ensure the bacterium's dissemination and prevalence. Their new findings are an important basis for the future management of the disease.
Read moreNew organelle that helps prevent cancer discovered in our cells
Scientists have discovered a strange structure inside our cells that helps to prevent cancer by ensuring genetic material is sorted correctly as cells divide. The discovery could improve treatment for breast cancer and possibly other cancers.
Read moreNew drug-delivery technology promises efficient, targeted cancer treatment
A precise and non-toxic treatment that targets lung cancer cells at the nanoscale is able to effectively kill the cells even at a low dose.
Read moreMen with breast cancer face high mortality rates
Men with breast cancer are more likely to die than their female counterparts, across all stages of disease, with the disparity persisting even when clinical characteristics, such as cancer types, treatment and access to care are considered, according to a new study.
Read moreHow the mouse X and Y chromosomes compete with each other to control offspring
New research presents the first demonstration of a specific difference in sperm function associated with sex ratio skewing.
Read moreBreaking the stroma barrier: Study shows a new way to hit cancer with radiation
Chemotherapy and radiation therapy are commonly used to treat cancer, but are not always effective and can have toxic side effects. Researchers tested a new radiotherapy technique that sends alpha-emitting particles to stroma cells in pancreatic tumors. The method slowed tumor growth in mice with minimal side effects, pointing to a new potential treatment option in the future for patients with pancreatic cancer.
Read moreGenes linked to sex ratio and male fertility in mice
Researchers find genes that help maintain the 50-50 balance between male and female offspring in mice — and that have major implications for male infertility.
Read moreA compound effective to chemotherapy-resistant cancer cells identified
A compound effective in killing chemotherapy-resistant glioblastoma-initiating cells (GICs) has been identified, raising hopes of producing drugs capable of eradicating refractory tumors with low toxicity.
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