Empty spaces, how do they make a protein unstable?

Partial unfolding of proteins can be a major challenge in the industry, as it may affect the stability of products. So how does an empty space or cavity in its hydrophobic core destabilize a protein? And would such a cavity, in fact, be empty? These are some of the questions that researchers answer in a new study.

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Controlling the charge state of organic molecule quantum dots in a 2D nanoarray

Researchers have fabricated a self-assembled, carbon-based nanofilm where the charge state (ie, electronically neutral or positive) can be controlled at the level of individual molecules. Molecular self-assembly on a metal results in a high-density, 2D, organic quantum-dot array with electric-field-controllable charge state, with the organic molecules used as 'nano-sized building blocks' in fabrication of functional nanomaterials. Achieved densities are an order of magnitude larger than conventional inorganic systems.

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Quantum paradox experiment may lead to more accurate clocks and sensors

More accurate clocks and sensors may result from a recently proposed experiment, linking an Einstein-devised paradox to quantum mechanics. A physicist said the international collaboration aimed to test Einstein's twin paradox using quantum particles in a 'superposition' state.

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How to control friction in topological insulators

Topological insulators are innovative materials that conduct electricity on the surface, but act as insulators on the inside. Physicists have begun investigating how they react to friction. Their experiment shows that the heat generated through friction is significantly lower than in conventional materials. This is due to a new quantum mechanism, the researchers report.

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Scientists pinpoint cause of harmful dendrites and whiskers in lithium batteries

Scientists have uncovered a root cause of the growth of needle-like structures — known as dendrites and whiskers — that plague lithium batteries, sometimes causing a short circuit, failure, or even a fire. Such defects are a major factor holding back the batteries from even more widespread use and further improvement.

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The nano-guitar string that plays itself

Scientists have created a nano-electronic circuit which vibrates without any external force. Just as a guitar string vibrates when plucked, the wire — 100,000 times thinner than a guitar string — vibrates when forced into motion by an oscillating voltage. The surprise came when they repeated the experiment without the forcing voltage. Under the right conditions, the wire oscillated of its own accord. The nano-guitar string was playing itself.

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Nanoscale manipulation of light leads to exciting new advancement

Controlling the interactions between light and matter has been a long-standing ambition for scientists seeking to develop and advance numerous technologies that are fundamental to society. With the boom of nanotechnology in recent years, the nanoscale manipulation of light has become both, a promising pathway to continue this advancement, as well as a unique challenge due to new behaviors that appear when the dimensions of structures become comparable to the wavelength of light.

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Powerful new genomics method can be used to reveal the causes of rare genetic diseases

The technique makes use of the fact that people inherit two copies or ''alleles'' of virtually every gene, one from the mother and one from the father. The new method compares activity levels of maternal and paternal alleles across the genome and detects when the activity of an allele lies far enough outside the normal range to be a plausible cause of disease.

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Physicists look to navigational 'rhumb lines' to study polymer's unique spindle structure

A new study describes how spheres can be transformed into twisted spindles thanks to insights from 16th century navigational tools. Researchers show how polymers can contract into spiral structures, known as loxodromes, that have complex patterning ten times smaller than the width of a human hair.

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