Researchers have developed an optical system that accurately measures the flow of extraordinarily tiny amounts of liquids — as small as 10 billionths of a liter (nanoliters) per minute.
Read moreFor the last 60 million years, fungus-growing ants have farmed fungi for food. In their cultivation of those fungi, they've successfully relied on bacteria-produced antimicrobial ingredients to protect their crops from other species of parasitic fungi. Now, researchers say they are looking to these ants to find new ways to stop or slow the evolution of antibiotic resistance that now presents a threat to modern medicine.
Read moreThe Global Program to Eliminate Lymphatic Filariasis delivers mass drug administration to 500 million people each year, and adverse events are common following treatment. Now, researchers have reported that certain changes in gene expression are associated with these adverse events.
Read moreUsing a new technique that can identify genetic profiles of individual cells, researchers modeled a breast cancer tumor's potential resistance to a drug, and then identified a drug combination that reversed that resistance.
Read moreFor new diabetes medications, in which one drug aims to address the excess of lipids and glucose in the blood, the therapeutic benefits, while great, frequently are accompanied by dangerous toxic effects to the heart. Why and how these drugs cause heart dysfunction in diabetes patients has been unclear. Now, scientists show that certain diabetes drugs have a profound toxic effect on the generation and function of mitochondria.
Read moreMichigan State University scientists have invented a new way to monitor chemotherapy concentrations, which is more effective in keeping patients' treatments within the crucial therapeutic window.
Read moreA unique new flexible and stretchable device, worn against the skin and capable of producing electrical energy by transforming the compounds present in sweat, was recently developed and patented. This cell is already capable of continuously lighting an LED, opening new avenues for the development of wearable electronics powered by autonomous and environmentally friendly biodevices.
Read moreScientists have developed a new class of antibiotic drug candidates which has high potential to be developed into a new generation of antibiotics fighting against multi-drug resistant superbugs including methicillin-resistant Staphylococcus aureus (MRSA).
Read moreScientists have succeeded in designing a compound to hook onto the pocket of the enzyme FTase and GGTase I, thereby inhibiting K-Ras. Scientists have worked to concoct an effective drug to target K-Ras proteins which cause cancer when they mutate. It is difficult to infiltrate K-Ras due to a lack of interactive pockets, so a strategy was devised to attack the necessary enzyme in the lipid modification of K-Ras.
Read moreOne of the WHO's 3 critical priority pathogens, Acinetobacter baumannii, for which new antibiotics are urgently needed is one step closer to being tackled, as researchers have made a breakthrough in understanding the enzymes that assemble the antibiotic enacyloxin.
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