Care for knee osteoarthritis in the United States
A new study provides an overview of US physicians' recommendations for physical therapy, lifestyle counseling, pain medications for treating knee osteoarthritis.
Read morePharmacology
Paclitaxel-coated devices are safe for unblocking arteries in lower limbs, study suggests
A study of nearly 65,000 people suggests that devices coated with a drug called paclitaxel that are used for widening blocked arteries in legs and feet are safe and not linked to an increase in deaths — a finding that contradicts smaller studies that led to the FDA issuing a safety alert about the use of paclitaxel-coated stents and balloons for arterial revascularization in the lower limbs in January 2019.
Read moreNew capsule can orally deliver drugs that usually have to be injected
MIT engineers designed a drug capsule that can carry insulin or other protein drugs and protect them from the harsh environment of the gastrointestinal tract. When the capsule reaches the small intestine, it breaks down to reveal dissolvable microneedles that attach to the intestinal wall and release drug for uptake into the bloodstream.
Read moreThe story of thalidomide continues
An international study has unveiled a detailed view of how thalidomide, one of the most notorious drugs ever developed, causes abnormalities in limb and ear development. The findings may contribute to the re-emergence of safe, or non-teratogenic, thalidomide-derived drugs as a treatment for cancer and inflammatory diseases.
Read moreScientists discover new antibiotic in tropical forest
Scientists have discovered an antibiotic produced by a soil bacterium from a Mexican tropical forest that may help lead to a 'plant probiotic,' more robust plants and other antibiotics. Probiotics, which provide friendlier bacteria and health benefits for humans, can also be beneficial to plants, keeping them healthy and more robust. The new antibiotic, known as phazolicin, prevents harmful bacteria from getting into the root systems of bean plants.
Read moreNew study is 'chilling commentary' on future of antibiotics
The health care market is failing to support new antibiotics used to treat some of the world's most dangerous, drug-resistant 'superbugs,' according to a new analysis.
Read moreBacteria trapped — and terminated — by graphene filter
Chemists transform their laser-induced graphene into an air filter that not only traps pathogens but also kills them with a small blast of electricity.
Read moreA breath test for opioids
A test to detect opioid drugs in exhaled breath has been developed by engineers and physicians. A breath test could be useful in caring for chronic pain patients as well as for checking for illegal drug use.
Read moreResearchers unlock potential to use CRISPR to alter the microbiome
Researchers have developed a new way to deliver the DNA-editing tool CRISPR-Cas9 into microorganisms in the lab, providing a way to efficiently launch a targeted attack on specific bacteria.
Read moreLong-term study data shows DBS is effective treatment for most severe form of depression
Deep brain stimulation (DBS) of an area in the brain called the subcallosal cingulate (SCC) provides a robust antidepressant effect that is sustained over a long period of time in patients with treatment-resistant depression — the most severely depressed patients who have not responded to other treatments.
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