More efficient drug delivery within the brain by utilizing LAT1
According to a new study the distribution of drug molecules within the brain can be improved by utilizing LAT1, which is expressed highly in the brain.
Read morePharmaceuticals
Probes shed new light on Alzheimer's cause
Researchers have found a way to track the formation of soluble amyloid beta peptide aggregates in lab samples. The aggregates are implicated in the onset of Alzheimer's disease.
Read moreNew reaction will make indoline scaffolds available for pharmaceutical development
New approach to producing indolent scaffolds could streamline development and production of small-molecule pharmaceuticals, which comprise the majority of medicines in use today.
Read moreDo the costs of cancer drugs receive enough attention?
A recent analysis from Canada found that information on health-related quality of life is often not collected for investigational cancer drugs or used to calculate the balance of costs and benefits of these drugs when they are submitted for reimbursement.
Read moreLong-acting injectable multi-drug implant shows promise for HIV prevention and treatment
UNC researchers have created an injectable multi-drug delivery system that is removable, biodegradable and effective for up to a year in some cases. The author says the ability to administer multiple drugs with this implant is an important advancement in this research.
Read moreInnovative candidate drug against malaria
A molecule once designed to cure the skin disease psoriasis appears to be particularly effective against malaria. The antimalarial properties were revealed thanks to one researcher's inspired hunch when the psoriasis drug discovery program came to a dead end. The candidate drug offers considerable potential for combating this infectious disease.
Read moreNew tool in fight against malaria
Modifying a class of molecules originally developed to treat the skin disease psoriasis could lead to a new malaria drug that is effective against malaria parasites resistant to currently available drugs.
Read morePreference for fentanyl higher among young, white, frequent opioid users
A minority of people who use illicit opioids indicated a preference for fentanyl, the super-potent synthetic opioid that accounts for much of the recent rise in US overdose deaths, according to a new study.
Read moreStudying proteins moving (relatively) slowly
Proteins keep our organs functioning, regulate our cells and are the targets for medications that treat a number of diseases, including cancers and neurological diseases. Proteins need to move in order to function. But, because the technology they used to watch proteins doesn't allow it, scientists still know very little about such motions at speeds slower than a nanosecond. That changed last month.
Read moreA safer way for police to test drug evidence
Scientists have demonstrated a way for police to quickly and safely test whether a baggie or other package contains illegal drugs without having to handle any suspicious contents directly. The new technique can limit the risk of accidental exposure to fentanyl and other highly potent drugs that can be dangerous if a small amount is accidentally inhaled.
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