Personalized Medicine – Page 7 – PossibleThreat Articles

First prostate cancer therapy to target genes delays cancer progression

October 1, 2019 0 Comments Breast Cancer, Cancer, Diseases and Conditions, Men's Health, Personalized Medicine, Prostate Cancer, Prostate Health, Urology

For the first time, prostate cancer has been treated based on the genetic makeup of the cancer, resulting in delayed disease progression, delayed time to pain progression, and potentially extending lives in patients with advanced, metastatic prostate cancer, reports a large phase 3 trial. This marks a significant advance for prostate cancer treatment, which has lagged behind other common cancers with regard to precision therapy, now the standard of care in breast, ovarian and lung cancers.

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Skin-cells-turned-to-heart-cells help unravel genetic underpinnings of cardiac function

September 30, 2019 0 Comments Diseases and Conditions, Genes, Heart Disease, Human Biology, Personalized Medicine, Stem Cells, Stroke Prevention, Vioxx

A small genetic study identified a protein linked to many genetic variants that affect heart function. Researchers are expanding the model to other organ systems and at larger scales to create a broader understanding of genes and proteins involved.

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First targeted therapy for cholangiocarcinoma shows clinical benefit in phase III trial

September 30, 2019 0 Comments Birth Defects, Diseases and Conditions, Lupus, Multiple Sclerosis Research, Patient Education and Counseling, Personalized Medicine, Today's Healthcare, Wounds and Healing

New data have shown for the first time that targeted therapy can improve the outcome of patients diagnosed with advanced cholangiocarcinoma. Cholangiocarcinoma is a subtype of bile duct cancer with aggressive behavior and poor prognosis. Despite the low incidence, most patients die from the disease and therefore new effective therapies are urgently needed.

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Handgun purchasers with a prior DUI have a greater risk for serious violence

September 30, 2019 0 Comments Anger Management, Consumer Behavior, Forensics, Justice, Legal Issues, Menopause, Personalized Medicine, Popular Culture, PTSD

Legal purchasers of handguns with a prior DUI conviction have a greater risk of a future arrest for a violent offense — including murder, rape, robbery, and aggravated assault and for firearm-related violent crimes.

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Whole genome sequencing could enable personalized cancer treatment

September 30, 2019 0 Comments Brain Tumor, Breast Cancer, Cancer, Colon Cancer, Lung Cancer, Pancreatic Cancer, Personalized Medicine, Skin Cancer

Whole genome sequencing of tumour cells could help predict the prognosis of a patient's cancer and offer clues to identify the most effective treatment, suggests an international study.

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Researchers advance search for safer, easier way to deliver vision-saving gene therapy

September 30, 2019 0 Comments Birth Defects, Diseases and Conditions, Eye Care, Gene Therapy, Genes, Medical Topics, Personalized Medicine, Viruses

In experiments with rats, pigs and monkeys, researchers have developed a way to deliver sight-saving gene therapy to the retina. If proved safe and effective in humans, the technique could provide a new, more permanent therapeutic option for patients with common diseases such as wet age-related macular degeneration (AMD), and it could potentially replace defective genes in patients with inherited retinal disease.

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New AI method may boost Crohn's disease insight and improve treatment

September 30, 2019 0 Comments Colitis, Crohn's Disease, Diseases and Conditions, Gastrointestinal Problems, Healthy Aging, Joint Pain, Pain Control, Personalized Medicine

Scientists have developed a computer method that may help improve understanding and treatment of Crohn's disease, which causes inflammation of the digestive tract. The study used artificial intelligence to examine genetic signatures of Crohn's in 111 people. The method revealed previously undiscovered genes linked to the disease, and accurately predicted whether thousands of other people had the disease.

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African American children respond differently to asthma medications

September 27, 2019 0 Comments Allergy, Asthma, Chronic Illness, Diseases and Conditions, Mental Health Research, Multiple Sclerosis Research, Personalized Medicine, Sickle Cell Anemia

African Americans suffer asthma more often and more severely than Caucasian patients. However, clinical trials that have shaped treatment guidelines have included few African Americans. A new report demonstrates a shortcoming of that history. Researchers report that African American children respond differently than African American adults and Caucasian adults and children to step-up therapies for inadequately controlled asthma.

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Genomic map implicates broad immune cell involvement in multiple sclerosis

September 27, 2019 0 Comments Brain-Computer Interfaces, Child Development, Diseases and Conditions, Disorders and Syndromes, Immune System, Multiple Sclerosis, Multiple Sclerosis Research, Personalized Medicine

In a study of 115,803 individuals, the authors have identified 233 sites or loci in the human genome that contribute to the onset of MS. This is the largest study to date in MS.

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Researchers uncover molecular changes associated with treating lymphatic filariasis

September 26, 2019 0 Comments Diseases and Conditions, Genes, Human Biology, Immune System, Lymphoma, Medical Topics, Personalized Medicine, Pharmacology

The Global Program to Eliminate Lymphatic Filariasis delivers mass drug administration to 500 million people each year, and adverse events are common following treatment. Now, researchers have reported that certain changes in gene expression are associated with these adverse events.