Three-hundred researchers have identified 48 common genetic variants that are associated with the size of the brainstem and other subcortical structures deep within the brain. This is the first step toward understanding how to devise treatments for disorders affecting these structures.
Read moreScientists have shown that delta waves emitted while we sleep are not generalized periods of silence during which the cortex rests, as has been described for decades in the scientific literature. Instead, they isolate assemblies of neurons that play an essential role in long-term memory formation.
Read moreResearchers used a grip-force test to analyze sensorimotor function in people with the FMR1 premutation, with the aim of determining FXTAS risk and severity.
Read moreUsing optogenetic and chemogenetic techniques, researchers have identified brain circuits underlying hunger-induced changes in the preferences for sweet and aversive tastes in mice. These circuits involved Agouti-related peptide-expressing neurons, which projected to glutamate neurons in the lateral hypothalamus. From there, glutamate neurons projecting to the lateral septum increased sweetness preferences, and glutamate neurons projecting to the lateral habenula decreased sensitivity to aversive tastes.
Read moreMilitary veterans with post-traumatic stress disorder or concussion suffer from a thrashing form of sleep behavior at a rate that is far higher than the general population, according to a new study. Researchers next want to probe whether the sleep disorder might provide an early signal of the development of neurodegenerative conditions such as Parkinson's disease.
Read moreResearchers haveidentified for the first time the initial steps of alpha-synuclein protein aggregates related to early onsets of hereditary Parkinson cases. The results may help the understanding of the early stages of the disease and how it develops over time.
Read moreFor years, scientists thought that these powerful sedatives, which are used to treat anxiety, muscle spasms, and sleeping disorders, worked alone to calm nerves. Now, researchers show that this view of the drugs and the neural circuits they affect may have to change. In a study of mice, scientists discovered that both may need the assistance of a 'sticky' gene, named after a mythological figure, called Shisa7.
Read moreUsing a fluorescent probe that lights up when brain cells are electrically active, researchers found they can image the activity of many neurons at once, in mice brains. The technique could allow neuroscientists to analyze circuits within the brain and link them to specific behaviors.
Read moreThe behavior of immune cells in the blood is so different in patients with Parkinson's disease that it advocate for a new type of supplementary medicine, which can regulate the immune system and thus inhibit the deterioration of the brain.
Read moreResearchers have identified a group of genetic variants related to the starting point of Parkinson's disease. These results, published in the journal Movement Disorders, will enable delimiting the research on new therapeutic targets, and could have implications in the diagnosis of the disease.
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