Scientists enlist tiny biomagnets for faster drug discovery
A new platform brings together CRISPR genome editing with magnetic cell sorting to reveal new drug targets for cancer and regenerative medicine.
Read moreOrganic Chemistry
Cracking the ethylene code
Separating pure ethylene from ethane is a difficult and costly process, but one that new research is poised to streamline. The technique would avoid liquefaction and distillation by designing a material that only binds ethylene molecules, thus separating them from ethane.
Read moreHow molecular footballs burst in an x-ray laser beam
An international research team has observed in real time how football molecules made of carbon atoms burst in the beam of an X-ray laser. The study shows the temporal course of the bursting process, which takes less than a trillionth of a second, and is important for the analysis of sensitive proteins and other biomolecules, which are also frequently studied using bright X-ray laser flashes.
Read moreNew reaction will make indoline scaffolds available for pharmaceutical development
New approach to producing indolent scaffolds could streamline development and production of small-molecule pharmaceuticals, which comprise the majority of medicines in use today.
Read moreScientists develop technique to observe radiation damage over femtoseconds
Scientists have developed a technique to observe how radiation damages molecules over time-frames of just one quadrillionth of a second — or a femtosecond.
Read moreDNA 'origami' takes flight in emerging field of nano machines
'DNA mechanotechnology' is a new field to engineer DNA machines that generate, transmit and sense mechanical forces at the nanoscale.
Read moreScientists develop DNA microcapsules with built-in ion channels
A Research group reports a way of constructing DNA-based microcapsules that hold great promise for the development of new functional materials and devices. They showed that tiny pores on the surface of these capsules can act as ion channels. Their study will accelerate advances in artificial cell engineering and molecular robotics, as well as nanotechnology itself.
Read moreDrug delivery: Thermo-responsive protein hydrogel
Bio-engineering researchers have created a biocompatible, protein-based hydrogel that could serve as a drug delivery system durable enough to survive in the body for more than two weeks while providing sustained medication release. The research advances an area of biochemistry that is also critical to tissue engineering and regenerative medicine. Protein hydrogels are more biocompatible than synthetic ones and do not require potentially toxic chemical crosslinkers.
Read moreScientists construct energy production unit for a synthetic cell
Scientists have constructed synthetic vesicles in which ATP, the main energy carrier in living cells, is produced. The vesicles use the ATP to maintain their volume and their ionic strength homeostasis. This metabolic network will eventually be used in the creation of synthetic cells – but it can already be used to study ATP-dependent processes.
Read moreElectronic nose can sniff out which lung cancer patients will respond to immunotherapy
An electronic nose that detects chemicals in the breath of lung cancer patients can identify with 85% accuracy those who will or will not respond to immunotherapy, according to new research.
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