'Artificial leaf' successfully produces clean gas


A widely-used gas that is currently produced from fossil fuels can instead be made by an 'artificial leaf' that uses only sunlight, carbon dioxide and water, and which could eventually be used to develop a sustainable liquid fuel alternative to gasoline.

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'Instant liver, just add water'? Not quite, but a better way to grow multiple organs

Pluripotent stem cells can be used to make experimental models of organ systems, but current techniques often produce models that bear limited resemblance to true organs. Researchers developed an improved method to make a sophisticated three-dimensional organoid model of the liver, pancreas, and bile ducts. The model may help researchers understand how these organs form and how genetic mutations can lead to diseases in these organs.

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Researchers quantify Cas9-caused off-target mutagenesis in mice

Scientists are finding new ways to improve the use of the CRISPR enzyme Cas9 and reduce the chances of off-target mutations in laboratory mice, according to new results. The findings will help scientists contextualize a common concern related to gene editing and identify new strategies to improve its precision.

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Scientists recalculate the optimum binding energy for heterogeneous catalysis

In a discovery that could lead to the development of novel catalysts that do not rely on expensive rare metals, scientists have shown that the optimal binding energy can deviate from traditional calculations, which are based on equilibrium thermodynamics, at high reaction rates. This means that reconsidering the design of catalysts using the new calculations may be necessary to achieve the best rates.

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A simpler way to make some medicines

Organic chemists have figured out how to synthesize the most common molecule arrangement in medicine, a scientific discovery that could change the way a number of drugs — including one most commonly used to treat ovarian cancer — are produced. Their discovery, published today in the journal Chem, gives drug makers a crucial building block for creating medicines that, so far, are made with complex processes that result in a lot of waste.

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Efficient synthesis of ginkgo compound could lead to new drugs, 'green' insecticides

Chemists have invented an efficient method for making a synthetic version of the plant compound bilobalide, which is naturally produced by gingko trees. It's a significant feat because bilobalide — and closely related compounds — hold potential commercial value as medicines and 'green' insecticides.

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