The 'Goldilocks' principle for curing brain cancer
Researchers found that a stable body temperature holds the key to awakening the body's immune response to fight off brain cancer.
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Targeting certain rogue T cells prevents and reverses multiple sclerosis in mice
Multiple sclerosis, an autoimmune disorder, is known to be driven by 'helper' T cells, white blood cells that mount an inflammatory attack on the brain and spinal cord. A new study pinpoints the specific subgroup of helper T cells that cause MS, as well as a protein on their surface, called CXCR6, that marks them. An antibody targeting CXCR6 both prevented and reversed MS in a mouse model, the researchers report.
Read moreScientists create brain-mimicking environment to grow 3D tissue models of brain tumors
Researchers have developed 3-dimensional human tissue culture models of pediatric and adult brain cancers in a brain-mimicking microenvironment, that includes brain-derived extracellular matrix (ECM) — the complex network of proteins and amino acids with bound sugars that not only provides support for surrounding neural tissue, but also helps to guide cell growth and development. The development represents a significant advancement for the study of brain tumor biology and pharmacological response.
Read moreStudy pinpoints Alzheimer's plaque emergence early and deep in the brain
By scanning whole brains of Alzheimer's model mice from an early age, researchers were able to precisely trace the terrible march of amyloid plaques from deep brain structures outward along specific circuits. They also showed that plaque density in a key region in humans scales with disease stage.
Read moreDealing a therapeutic counterblow to traumatic brain injury
A team of biomedical engineers are developing a therapy which shows early indications it can protect neurons and stimulate the regrowth of blood vessels in damaged tissue.
Read moreMounting brain organoid research reignites ethical debate
As research involving the transplantation of human 'mini-brains' — known as brain organoids — into animals to study disease continues to expand, so do the ethical debates around the practice. A new article seeks to clarify the abilities of brain organoids and suggests an ethical framework that better defines and contextualizes these organoids and establishes thresholds for their use.
Read moreWhy the language-ready brain is so complex
Scientists argue for a new model of language, involving the interaction of multiple brain networks. This model is much more complex than the classical neurobiological model of language, which was largely based on single-word processing.
Read moreGolden ratio observed in human skulls
The Golden Ratio, described by Leonardo da Vinci and Luca Pacioli as the Divine Proportion, is an infinite number often found in nature, art and mathematics. It's a pattern in pinecones, seashells, galaxies and hurricanes.
Read moreDrops in income may not only hurt the wallet, they may harm the brain
Young adults who experience annual income drops of 25% or more may be more at risk of having thinking problems and reduced brain health in middle age, according to a new study.
Read moreResearchers identify molecular process that could accelerate recovery from nerve injuries
Researchers have discovered a molecular process that controls the rate at which nerves grow both during embryonic development and recovery from injury throughout life.
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