How the brain dials up the volume to hear someone in a crowd

Our brains have a remarkable ability to pick out one voice from among many. Now, a team has uncovered the steps that take place in the brain to make this feat possible. Today's discovery helps to solve a long-standing scientific question as to how the brain's listening center can decode and amplify one voice over others. It also stands to spur development of hearing-aid technologies and brain-computer interfaces that more closely resemble the brain.

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Unique brain changes in people with Huntington's disease

The part of the brain that selectively degenerates in people with Huntington's disease (HD), called the striatum, is almost entirely destroyed in the late stages of the disease. Brain samples from mutant HD gene positive individuals who had not yet developed symptoms by time of death are extremely rare. As a consequence, very little is known about the active disease process that causes the devastating symptoms of HD.

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The night gardeners: Immune cells rewire, repair brain while we sleep

Science tells us that a lot of good things happen in our brains while we sleep — learning and memories are consolidated and waste is removed, among other things. New research shows for the first time that important immune cells called microglia — which play an important role in reorganizing the connections between nerve cells, fighting infections, and repairing damage — are also primarily active while we sleep.

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Novel nanoprobes show promise for optical monitoring of neural activity

Researchers have developed ultrasensitive nanoscale optical probes to monitor the bioelectric activity of neurons and other excitable cells. This novel readout technology could enable scientists to study how neural circuits function at an unprecedented scale by monitoring large numbers of individual neurons simultaneously. It could also lead to high-bandwidth brain-machine interfaces with dramatically enhanced precision and functionality.

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A new discovery: How our memories stabilize while we sleep

Scientists have shown that delta waves emitted while we sleep are not generalized periods of silence during which the cortex rests, as has been described for decades in the scientific literature. Instead, they isolate assemblies of neurons that play an essential role in long-term memory formation.

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