Quality control in immune communication: Chaperones detect immature signaling molecules

The cells of our immune system constantly communicate with one another by exchanging complex protein molecules. A team has now revealed how dedicated cellular control proteins, referred to as chaperones, detect immature immune signaling proteins and prevent them from leaving the cell.

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Most California wildfire is in wildland-urban interface area with less fuel, more people

Homeowner guidance and fire behavior models are largely based on the idea that natural grass, bushes and trees fuel fire in the wildland-urban interface (WUI). Researchers found that over nearly three decades, half of all buildings destroyed by wildfire in California were located in an area of the WUI with less natural vegetation.

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Researchers perform thousands of mutations to understand amyotrophic lateral sclerosis

Researchers have used a technique called high-throughput mutagenesis to study Amyotrophic Lateral Sclerosis (ALS), with unexpected results. Results showed that aggregation of TDP-43 is not harmful but actually protects cells, changing our understanding of ALS and opening the door to radically new therapeutic approaches.

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How people with psychopathic traits control their 'dark impulses'

How do people with psychopathic traits control their 'dark impulses?' A team of researchers are finding answers in levels of gray matter density in the ventrolateral prefrontal cortex, a region of the brain involved in the regulation of emotions, including fear and anger.

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Neurological signals from the spinal cord surprise scientists

With a study of the network between nerve and muscle cells in turtles, researchers have gained new insight into the way in which movements are generated and maintained. In the long term, the new knowledge may have an impact on the treatment of, for example, ALS and spinal cord injuries.

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Learning to read boosts the visual brain

How does learning to read change our brain? Does reading take up brain space dedicated to seeing objects such as faces, tools or houses? In a functional brain imaging study, a research team compared literate and illiterate adults in India. Reading recycles a brain region that is already sensitive to evolutionarily older visual categories, enhancing rather than destroying sensitivity to other visual input.

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