Researchers investigate key component in bacteria

A protective protein that detects newly-made incomplete protein chains in higher cells is found to have a relative in bacteria. There, the protein also plays a central role in quality control which ensures that defective proteins are degraded. The functional mechanism of these Rqc2 proteins must therefore have already existed several billion years ago in the so-called last universal common ancestor. Scientists have experimentally investigated the bacterial Rqc2 relative's function.

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Using unconventional materials, like ice and eggshells, as scaffolds to grow tissues

Researchers explore recent efforts to use everyday materials like ice, paper, and spinach as tissue scaffolds. These unconventional materials, they argue, are more functional, more sustainable, and less expensive, as well as being available around the globe and applicable to many areas of biomedical research.

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Studying proteins moving (relatively) slowly

Proteins keep our organs functioning, regulate our cells and are the targets for medications that treat a number of diseases, including cancers and neurological diseases. Proteins need to move in order to function. But, because the technology they used to watch proteins doesn't allow it, scientists still know very little about such motions at speeds slower than a nanosecond. That changed last month.

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Scientists construct energy production unit for a synthetic cell

Scientists have constructed synthetic vesicles in which ATP, the main energy carrier in living cells, is produced. The vesicles use the ATP to maintain their volume and their ionic strength homeostasis. This metabolic network will eventually be used in the creation of synthetic cells – but it can already be used to study ATP-dependent processes.

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Synthetic cells capture and reveal hidden messages of the immune system

New research is highly relevant to how antibodies are made in response to infections, vaccines and in autoimmunity due to the its analysis of a signal that is associated with hyper IgM syndrome, a genetic deficiency of CD40 ligand (CD40L) that results in profound immunodeficiency.

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