For the first time, researchers have captured images of the formation of individual viruses, offering a real-time view into the kinetics of viral assembly. The research provides new insights into how to fight viruses and engineer self-assembling particles.
Read moreAntibiotics are still the most important weapon for combatting bacterial infections. But medical science is running out of ''ammunition'' because of more and more frequently occurring resistances. Research teams have now elucidated the structure of the proteolytic complex ClpX-ClpP. This is a key to development of innovative antibiotics which target the degradation process of defective proteins in bacteria.
Read moreFor the first time, researchers have learned at the molecular level how the P2X7 protein receptor – which is associated with inflammation, coronary artery disease, cancer, multiple sclerosis and more – works. The findings could one day inspire new drugs to treat numerous medical conditions.
Read moreResearchers have uncovered a chromosome-wide mechanism that keeps the gene expression of sex chromosomes in balance in our cells. The findings shed light on molecular reasons for early miscarriage and could be important for the emerging field of regenerative medicine.
Read moreScientists have created the most accurate 3D model yet of an intrinsically disordered protein, revealing the ensemble of its atomic-level structures.
Read moreScientists have now succeeded in using high-resolution imaging to make visible to the millisecond how the HI virus spreads between living cells and which molecules it requires for this purpose. The researchers provide direct proof for the first time that the AIDS pathogen creates a certain lipid environment for replication.
Read moreNuclear abnormalities such as nuclear blebs and micronuclei have devastating consequences for the genetic material and are associated with cancer or ageing. Scientists now revealed that the epigenetic enzyme MOF is crucial for the morphological integrity of the mammalian nucleus. Moreover, the study characterized the epigenetic landscape of nuclear abnormalities and discovered a formerly unknown epigenetic mechanism that seems to protect cells from additional damage.
Read moreResearchers have identified and confirmed the gene responsible for lutein esterification in bread wheat. The activity of this gene controls the timing of esterification in grain, which is related to storage and nutritional qualities of bread wheat and other grains.
Read moreEngineers have shown that the length of collagen fibers has a roll to play in the ability of normal cells to become invasive.
Read moreFor the first time ever, a professor has observed a crystallized iron product called hemozoin being made in mammals, with widespread implications for future research and treatment of blood disorders. Findings could be used to treat sickle cell disease and malaria patients, while opening up diverse research avenues across immunology, parasitology, neuroscience, microbiology, and even urology.
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