For the first time, researchers have captured images of the formation of individual viruses, offering a real-time view into the kinetics of viral assembly. The research provides new insights into how to fight viruses and engineer self-assembling particles.
Read moreAntibiotics are still the most important weapon for combatting bacterial infections. But medical science is running out of ''ammunition'' because of more and more frequently occurring resistances. Research teams have now elucidated the structure of the proteolytic complex ClpX-ClpP. This is a key to development of innovative antibiotics which target the degradation process of defective proteins in bacteria.
Read moreWound inflammation which results in impaired wound healing can have serious consequences for patients. Researchers have discovered a new defensive mechanism which enables our skin to actively kill bacteria. Central to this mechanism is a cellular messenger molecule known as 'interleukin 6', whose mode of action may be used in the future to prevent wound infections.
Read moreThe spread of antibiotic resistant genes (ARGs) through the water system could put public safety at-risk. Researchers studied and compared samples from an advanced groundwater treatment facility in California and groundwater aquifers to detect differences in ARG concentrations. They found that the advanced groundwater treatment facility reduced nearly all targeted ARGs to below detection limits, but groundwater samples had a ubiquitous presence of ARGs in both control locations and locations recharged with water from the advanced water treatment facility.
Read moreShiga toxin subtype 2a (Stx2a) may play a key role in promoting the colonization and transmission of life-threatening Escherichia coli strains in cattle, according to a new study.
Read moreBiological engineers can program bacteriophages to kill different strains of E. coli by making mutations in the protein that the viruses use to bind to host cells. These engineered phages are less likely to provoke resistance in bacteria, and could help to overcome antibiotic resistance.
Read moreTaking a 'fingerprint' of the mix of bacteria in the gut can indicate how susceptible individual cancer patients are to gut damage as a result of radiotherapy for prostate and gynaecological cancers, a new study shows. Researchers showed that having a reduced diversity of gut bacteria was associated with an increased risk of both immediate and delayed damage to the gut following radiotherapy.
Read moreCertain fungi move from the gut to the pancreas, expand their population more than a thousand-fold, and encourage pancreatic cancer growth, a new study finds.
Read moreResearchers have analyzed remains from ten archaeological sites in England, France, Germany, Russia, and Switzerland to gain insight into the different stages of the second plague pandemic and the genetic diversity of Yersinia pestis during and after the Black Death. The researchers reconstructed 34 Y. pestis genomes, tracing the genetic history of the bacterium, which revealed key insights into the initiation and progression of the second plague pandemic in Europe.
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