Researchers have discovered how to pre-program microfluidic systems in a way that controls how fluids flow and mix throughout the micropipes. The result? A step toward smartly designed microfluidic systems that behave like a computer chip without relying on external components.
Read moreA group of scientists have developed a new technology that makes it possible to rapidly identify viruses in wheat fields with a significantly higher accuracy. They collected four wheat samples from western Kansas and used a new harmonica-sized DNA sequencer and a computer program to quickly detect three different viruses in the samples. Furthermore, their results suggested that the samples contained a new virus strain.
Read moreScientists are finding new ways to improve the use of the CRISPR enzyme Cas9 and reduce the chances of off-target mutations in laboratory mice, according to new results. The findings will help scientists contextualize a common concern related to gene editing and identify new strategies to improve its precision.
Read moreThe entry probe of the Galileo mission to Jupiter entered the planet's atmosphere in 1995 in fiery fashion, generating enough heat to cause plasma reactions on its surface. The data relayed about the burning of its heat shield differed from the effects predicted in fluid dynamics models, and new work examines what might have caused such a discrepancy. Researchers now report their findings from new fluid radiative dynamics models.
Read moreCurrent testing for Lyme disease, called the standard 2-tiered approach or the STT, involves running two complex assays (ELISA and western blot) to detect antibodies against the bacterium, and requires experienced personnel in a lab, and a few hours to carry out and interpret. Biomedical engineers have developed a rapid microfluidic test that can detect Lyme disease with similar performance as the STT in a much shorter time — 15 minutes.
Read moreRecent advances in fluorescence microscopy allow researchers to study biological processes below the classical diffraction limit of light. Researchers have now developed DNA-PAINT, a variant of these so-called super-resolution approaches.
Read moreThe technique makes use of the fact that people inherit two copies or ''alleles'' of virtually every gene, one from the mother and one from the father. The new method compares activity levels of maternal and paternal alleles across the genome and detects when the activity of an allele lies far enough outside the normal range to be a plausible cause of disease.
Read moreIf you've ever stopped to watch rain falling on a windowpane, you've seen what happens when two drops of water touch and merge into one. But you probably never imagined that the physics at work in this phenomenon was the key to unlocking a solution for the development of miniaturized personal biological analysis devices.
Read moreScientists have successfully used microneedle biosensors to accurately detect changes in antibiotic levels in the body, for the first time.
Read moreResearchers have found that steps measured through a step tracker worn on the wrist can be used to estimate exercise capacity and determine the health status of patients, rather than the standardized 6-minute walk distance test, which is usually conducted in a clinical setting.
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