In response to seizures, the endoplasmic reticulum (ER), a network of flattened tubes in the cell that packages and transports proteins, triggers a stress response that reduces brain activity and seizure severity. The new findings may have important implications for the development of new epilepsy therapies.
Read moreTwo studies provide evidence for the impact of biology by using artificial intelligence to identify patterns of brain activity that make people less responsive to certain antidepressants. Put simply, scientists showed they can use imaging of a patient's brain to decide whether a medication is likely to be effective.
Read moreIntestinal epithelial cells (IECs) are exposed to diverse types of environmental stresses such as bacteria and toxins, but the mechanisms by which epithelial cells sense stress are not well understood. New research has found that Nox-ROS-ASK1-MKK3-p38 signaling in IECs integrates various stresses to facilitate intestinal regeneration.
Read moreThree new studies highlight the relationship between air pollution and mental health in children.
Read moreNew research suggests that depression and binge-drinking are more common among the female partners of UK military personnel than among comparable women outside the military community.
Read moreCurrent obesity rates in adults in the United States could be the result of dietary changes that took place decades ago, according to a new study.
Read moreEven mild long-term depressive symptoms among mothers are connected with emotional problems among small children such as hyperactivity, aggressiveness and anxiety.
Read moreThough research shows that medication-assisted treatment can help people who are addicted to opioids, the three drugs approved by the Food and Drug Administration (FDA) are underused, according to a review of current medical data on opioid addiction in the U.S.
Read moreWhen does childhood end? That's the question international researchers are asking as they chart age cut-offs for paediatric services around the world. Previous research has found that global health systems do not meet adolescents' needs, yet pediatricians are well placed to provide age-appropriate care to adolescents — especially if they are trained in adolescent medicine.
Read moreIndividuals raised in families with higher socioeconomic status were more optimistic in midlife, and in turn, lived longer. Those who experienced more psychosocial stressors, such as parental death, frequent moves and harsh discipline, tended to encounter more stressful life events in midlife, and had greater risk of dying early.
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