Point-of-care diagnostic for detecting preterm birth on horizon

A new study provides a first step toward the development of an inexpensive point-of-care diagnostic test to assess the presence of known risk factors for preterm birth in resource-poor areas. The study found that measuring levels of TIMP-1 and D-lactic acid in vaginal secretions may be a noninvasive, cost-effective way to assess the risk for preterm birth due to a short cervix and microbiome composition.

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The spectrum of arrogance

A team of psychology researchers is providing one of the first comprehensive literature reviews on arrogance, as well as a way to classify the condition on different levels across a spectrum, similarly to how autism is diagnosed. The team acknowledges everyone seems to have some degree of arrogance, so in addition to the literature review, the researchers suggest a way to classify the different levels of arrogance a person could exhibit.

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Exploring the effect of fasting on age-related diseases

There are many indications that fasting promotes longevity. In recent years, much attention has been devoted to so-called caloric restriction mimetics (CMRs), substances that simulate the health-promoting effects of fasting without the need of life-style change. A study reports the identification of a novel candidate CRM. The substance may prove useful in the further research for the treatment of age-related diseases.

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'Instant liver, just add water'? Not quite, but a better way to grow multiple organs

Pluripotent stem cells can be used to make experimental models of organ systems, but current techniques often produce models that bear limited resemblance to true organs. Researchers developed an improved method to make a sophisticated three-dimensional organoid model of the liver, pancreas, and bile ducts. The model may help researchers understand how these organs form and how genetic mutations can lead to diseases in these organs.

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