Lymphoma – Page 9 – PossibleThreat Articles

Discovery of novel cancer signaling mechanism and design of new anticancer compound

September 23, 2019 0 Comments Brain Tumor, Breast Cancer, Cancer, Colon Cancer, Leukemia, Lung Cancer, Lymphoma, Skin Cancer

Active mutations of a certain signaling receptor protein called KIT tyrosine kinase are found in several cancers, such as acute myeloid leukemia (AML). However, the different locations in the AML cells where KIT induces cancer-specific signaling remain unclear. Now, a group of scientists has aimed to answer this question by using a newly synthesized compound (along with other existing ones) that targets intracellular transport, which may offer an attractive strategy to combat cancer.

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New mechanism for dysfunctional insulin release identified

September 19, 2019 0 Comments Anemia, Brain Tumor, Diabetes, Hormone Disorders, Hypertension, Immune System, Lymphoma, Vitamin D

Researchers have identified a previously unknown mechanism that regulates release of insulin, a hormone that lowers blood glucose levels, from the beta cells of the pancreas. This mechanism is disrupted in type 2 diabetes. The scientists hope this finding will be used to develop new treatments against the disease.

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Combination therapies could help treat fatal lung cancers

September 18, 2019 0 Comments Brain Tumor, Breast Cancer, Cancer, Colon Cancer, Lung Cancer, Lung Disease, Lymphoma, Skin Cancer

Combining a new class of drug with two other compounds can significantly shrink lung tumors in mice and human cancer cells, new research shows. The study looked at G12C KRAS inhibitors, a new type of drug that targets a specific mutation that can cause cells to multiply uncontrollably and lead to fast-growing cancers.

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New drug target in fight against cancer

September 18, 2019 0 Comments Brain Tumor, Breast Cancer, Cancer, Colon Cancer, Diseases and Conditions, Leukemia, Lung Cancer, Lymphoma

Researchers have discovered how a cancer-linked version of the protein mitoNEET can close voltage-dependent anion channels (VDAC), primary gateways in the outer surface of mitochondria. The researchers detail how mitoNEET regulates VDAC, and they show that the interactions between the two proteins could be disrupted by a drug that targets VDAC.

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New factor in the development of childhood lymphoma

September 18, 2019 0 Comments Diseases and Conditions, HIV and AIDS, Human Biology, Immune System, Lupus, Lymphoma, Medical Topics, Viruses

The immune system is highly complex and a detailed understanding of many underlying mechanisms is still lacking. Only the precise interaction of a variety of factors guarantees a reliable and correct immune response in a healthy body. Misregulated immune responses are a major cause of a variety of diseases, including cancer, autoimmunity, and immune deficiency.

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Cancer cells turn to cannibalism to survive chemotherapy, study suggests

September 18, 2019 0 Comments Brain Tumor, Breast Cancer, Cancer, Colon Cancer, Leukemia, Lung Cancer, Lymphoma, Prostate Cancer

Researchers have discovered that some cancer cells survive chemotherapy by eating their neighboring tumor cells. The study suggests that this act of cannibalism provides these cancer cells with the energy they need to stay alive and initiate tumor relapse after the course of treatment is completed.

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Autoantibodies in pregnancy: A cause of behavioral disorders in the child?

September 18, 2019 0 Comments Birth Defects, Brain Tumor, Children's Health, Diseases and Conditions, Immune System, Lymphoma, Nervous System, Pregnancy and Childbirth

Dysfunctions in the maternal immune system that occur during pregnancy could possibly lead to impaired brain development in the unborn child.

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Radiation may lower potential for side effects of CAR T therapy in non-hodgkin's lymphoma

September 18, 2019 0 Comments Colon Cancer, Diseases and Conditions, Gene Therapy, Lymphoma, Medical Imaging, Personalized Medicine, Today's Healthcare, Wounds and Healing

Treating non-Hodgkin's lymphoma (NHL) patients with radiation therapy as an additional treatment while they wait for their CAR T cells to be manufactured may reduce the risk of CAR T therapy side effects once it is administered.

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Kidney disease: Senescent cell burden is reduced in humans by senolytic drugs

September 18, 2019 0 Comments Cancer, Chronic Illness, Diseases and Conditions, Healthy Aging, Immune System, Lung Cancer, Lymphoma, Stem Cells

In a small safety and feasibility clinical trial, researchers have demonstrated for the first time that senescent cells can be removed from the body using drugs termed 'senolytics.' The result was verified not only in analysis of blood but also in changes in skin and fat tissue senescent cell abundance.

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Synthetic cells capture and reveal hidden messages of the immune system

September 17, 2019 0 Comments Biology, Biotechnology, Biotechnology and Bioengineering, Immune System, Lymphoma, Medical Topics, Molecular Biology, Stem Cells

New research is highly relevant to how antibodies are made in response to infections, vaccines and in autoimmunity due to the its analysis of a signal that is associated with hyper IgM syndrome, a genetic deficiency of CD40 ligand (CD40L) that results in profound immunodeficiency.