Men with breast cancer are more likely to die than their female counterparts, across all stages of disease, with the disparity persisting even when clinical characteristics, such as cancer types, treatment and access to care are considered, according to a new study.
Read moreIn a novel study comparing healthy cells from people in their 20s with cells from people in their 80s, researchers say they have documented that cell division rates appear to consistently and markedly slow down in humans at older ages.
Read moreChemotherapy and radiation therapy are commonly used to treat cancer, but are not always effective and can have toxic side effects. Researchers tested a new radiotherapy technique that sends alpha-emitting particles to stroma cells in pancreatic tumors. The method slowed tumor growth in mice with minimal side effects, pointing to a new potential treatment option in the future for patients with pancreatic cancer.
Read morePhagocytosis can be viewed as a primitive immune system used by all cells. When a pathogen is near the cell, the cell membrane will deform to engulf the pathogen and dispose of it. Researchers have found that a two-dimensional sheet formed by the protein GAS7 is critical for this process, identifying through crystallography and microscopy two key hydrophilic loops in the protein.
Read moreThe study, conducted in mice, is the first to show that creatine uptake is critical to the anti-tumor activities of killer T cells, the foot soldiers of the immune system.
Read moreResearchers have developed a new cheap method that can identify highly heterogeneous tumors that tend to be very aggressive, and therefore need to be treated more aggressively.
Read moreResearchers provide clearer picture of how lungs develop and discover novel markers to differentiate populations of lung cells implicated in lung diseases of premature babies.
Read moreA compound effective in killing chemotherapy-resistant glioblastoma-initiating cells (GICs) has been identified, raising hopes of producing drugs capable of eradicating refractory tumors with low toxicity.
Read moreOrganic chemists have figured out how to synthesize the most common molecule arrangement in medicine, a scientific discovery that could change the way a number of drugs — including one most commonly used to treat ovarian cancer — are produced. Their discovery, published today in the journal Chem, gives drug makers a crucial building block for creating medicines that, so far, are made with complex processes that result in a lot of waste.
Read moreFor the first time, researchers have created mouse blastocyst-like structures, or 'blastoids,' from a single cultured cell. The work could help advance research into development as well as inform issues around pregnancy, infertility, or health problems later in the offspring's life.
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