Liver Disease – PossibleThreat Articles

Deleting a liver enzyme lowers the health risk of sweet treats (at least in mice)

October 24, 2019 0 Comments Cholesterol, Diabetes, Diet and Weight Loss, Diseases and Conditions, Hypertension, Liver Disease, Obesity, Personalized Medicine

Hepatic insulin resistance, caused by diets high in sugar and fat, can lead to type 2 diabetes. Researchers found that the Elovl6 gene plays a key role in hepatic insulin resistance. Deleting Elov6 in liver cells causes a rise in a specific ceramide lipid that protects mice from hepatic insulin resistance due to excessive dietary sugar. The findings could help efforts to find a targeted treatment for the condition.

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Immune reaction causes malaria organ damage

October 21, 2019 0 Comments Heart Disease, Immune System, Liver Disease, Malaria, mice, Microbiology, Pests and Parasites, rodents

Immune cells can be the body's defenders and foes at the same time.

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'Instant liver, just add water'? Not quite, but a better way to grow multiple organs

October 21, 2019 0 Comments Biochemistry, Liver Disease, Medical Technology, Medical Topics, Organic Chemistry, Pancreatic Cancer, Solar Energy, Stem Cells

Pluripotent stem cells can be used to make experimental models of organ systems, but current techniques often produce models that bear limited resemblance to true organs. Researchers developed an improved method to make a sophisticated three-dimensional organoid model of the liver, pancreas, and bile ducts. The model may help researchers understand how these organs form and how genetic mutations can lead to diseases in these organs.

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Cell family trees tracked to discover their role in tissue scarring and liver disease

October 16, 2019 0 Comments Chronic Illness, Cosmetics, Diseases and Conditions, Liver Disease, Lymphoma, Prostate Cancer, Stem Cells, Today's Healthcare

Researchers have discovered that a key cell type involved in liver injury and cancer consists of two cellular families with different origins and functions.

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Drug reverses signs of liver disease in people living with HIV

October 12, 2019 0 Comments Chronic Illness, Diseases and Conditions, HIV and AIDS, Infectious Diseases, Liver Disease, Sexual Health, STD, Today's Healthcare

Researchers report that the injectable hormone tesamorelin reduces liver fat and prevents liver fibrosis (scarring) in people living with HIV.

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Sox9 reshapes the biliary tree in Alagille syndrome

October 11, 2019 0 Comments Birth Defects, Children's Health, Chronic Illness, Diseases and Conditions, Down Syndrome, Gene Therapy, Liver Disease, Today's Healthcare

Mose model shows that SOX9 gene influences the severity Alagille syndrome.

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First cell map of developing human liver reveals how blood and immune system develops

October 9, 2019 0 Comments Brain Tumor, Diseases and Conditions, Immune System, Leukemia, Liver Disease, Lymphoma, Medical Topics, Stem Cells

In a world first, scientists have created the human developmental liver cell atlas that provides crucial insights into how the blood and immune systems develop in the fetus. It maps changes in the cellular landscape of the developing liver between the first and second trimesters of pregnancy, including how stem cells from the liver seed other tissues to support the high demand for oxygen needed for growth.

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Fresh insights could lead to new treatments for liver disease

October 9, 2019 0 Comments Chronic Illness, Diseases and Conditions, Heart Disease, Immune System, Liver Disease, Lymphoma, Stem Cells, Today's Healthcare

The fight against liver disease could be helped by the discovery of cells that cause liver scarring.

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Potential liver cancer treatment by targeting cancer stem-like cells

October 9, 2019 0 Comments Brain Tumor, Breast Cancer, Cancer, Colon Cancer, Liver Disease, Lung Cancer, Prostate Cancer, Skin Cancer

Researchers have shown the potential use of small molecule inhibitors to treat advanced liver cancer.

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New mechanism in the liver helps prevent invasive fungal infections

October 8, 2019 0 Comments Chronic Illness, Diseases and Conditions, Fungus, Kidney Disease, Liver Disease, Microbes and More, Microbiology, Organic

An expert in intravital microscopy is making breakthroughs in invasive fungal infections. He has discovered a pathway by which liver macrophages capture fungi before dissemination to target organs like the brain. This not only provides an explanation as to why individuals with liver disease have enhanced risk of fungal infection, but also points to therapeutic options to prevent these infections, which kill 1.5 million people annually.

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