How neuronal migration and outgrowth shape network architecture

Neurons are not randomly arranged in the human brain. In the cortex, they are organized in interconnected clusters with high intrinsic connectivity. This modular connectivity structure, in which clusters eventually serve as functional units, is formed in early phases of development. The underlying self-organization process is regulated by neuronal activity but the detailed mechanisms are still poorly understood. Based on in vitro studies and computational modeling, neuroscientists have now made an important contribution to the understanding of brain networks and their development: in their current study, they show how neuronal outgrowth and migration interact in shaping network architecture and the degree of modularity in mature networks.

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Mild-to-moderate hearing loss in children leads to changes in how brain processes sound

Deafness in early childhood is known to lead to lasting changes in how sounds are processed in the brain, but new research published today shows that even mild-to-moderate levels of hearing loss in young children can lead to similar changes.

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Neuroimaging reveals hidden communication between brain layers during reading

Language involves many different regions of the brain. Researchers have discovered previously hidden connections between brain layers during reading, in a neuroimaging study. The team used laminar Functional Magnetic Resonance Imaging (lfMRI) to investigate what happens when people read Dutch words like ''zalm'' (salmon) compared to pseudowords (''rorf''), revealing top-down influences on deep brain layers for the first time.

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