Protective mediators can help heal injured tendon cells by attacking inflammation

Tendon tears, both to the rotator cuff and Achilles heel, are common injuries, especially in aged individuals. Painful and disabling, they can adversely impact quality of life. New approaches are required to help patients suffering from chronic tendon injuries. A novel study identified mediators that promote resolution of inflammation as potential new therapeutics to push chronically injured tendons down an inflammation-resolving pathway.

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New AI method may boost Crohn's disease insight and improve treatment

Scientists have developed a computer method that may help improve understanding and treatment of Crohn's disease, which causes inflammation of the digestive tract. The study used artificial intelligence to examine genetic signatures of Crohn's in 111 people. The method revealed previously undiscovered genes linked to the disease, and accurately predicted whether thousands of other people had the disease.

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Therapeutic strategies for pregnant women with lupus

A highly gender-biased disease, lupus afflicts females some nine times more than males. Because of the disease's unpredictable turns and debilitating flares — the risks of which are elevated in postpartum women — females with the disease are often advised to avoid pregnancy altogether.

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