Young infants with fever may be more likely to develop infections
Infants with a high fever may be at increased risk for infections, according to new research.
Read moreInfectious Diseases
Weak spot in pathogenic bacteria
Antibiotics are still the most important weapon for combatting bacterial infections. But medical science is running out of ''ammunition'' because of more and more frequently occurring resistances. Research teams have now elucidated the structure of the proteolytic complex ClpX-ClpP. This is a key to development of innovative antibiotics which target the degradation process of defective proteins in bacteria.
Read moreResearchers unlock potential to use CRISPR to alter the microbiome
Researchers have developed a new way to deliver the DNA-editing tool CRISPR-Cas9 into microorganisms in the lab, providing a way to efficiently launch a targeted attack on specific bacteria.
Read moreAnalysis of HIV-1B in Indonesia illuminates transmission dynamics of the virus
Research into the molecular phylogeny (evolutionary history) of the HIV-1B virus in Indonesia has succeeded in illuminating the transmission period and routes for three clades (main branches of the virus). This includes a clade thought to be unique to Indonesia, as well as clades that spread from Thailand, Europe and America in the 1970s and 1980s.
Read moreNew test assists physicians with quicker treatment decisions for sepsis
A new test to determine whether antibiotics will be effective against certain bacterial infections is helping physicians make faster and better prescription treatment choices.
Read moreHow the influenza virus achieves efficient viral RNA replication
Researchers offer new insights on how subunits of the influenza virus polymerase co-evolve to ensure efficient viral RNA replication.
Read moreEngineered viruses could fight drug resistance
Biological engineers can program bacteriophages to kill different strains of E. coli by making mutations in the protein that the viruses use to bind to host cells. These engineered phages are less likely to provoke resistance in bacteria, and could help to overcome antibiotic resistance.
Read moreIn women with HIV, TB preventive therapy poses greater risk in pregnancy than postpartum
Study results help clarify how to safely prevent tuberculosis (TB) in women living with HIV who are pregnant or have recently given birth, are taking antiretroviral therapy, and live where TB is highly prevalent.
Read moreMost kidney transplants between people with HIV have long-term success
People living with HIV who received kidney transplants from deceased donors with HIV had high rates of overall survival and kidney graft survival after five years, according to an observational study. The investigators followed 51 study participants with HIV who received kidney transplants from deceased donors with HIV in South Africa.
Read moreHow AIDS pathogens multiply in the body
Scientists have now succeeded in using high-resolution imaging to make visible to the millisecond how the HI virus spreads between living cells and which molecules it requires for this purpose. The researchers provide direct proof for the first time that the AIDS pathogen creates a certain lipid environment for replication.
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