Drug reverses signs of liver disease in people living with HIV
Researchers report that the injectable hormone tesamorelin reduces liver fat and prevents liver fibrosis (scarring) in people living with HIV.
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A reliable clock for your microbiome
The microbiome is a treasure trove of information about human health and disease, but getting it to reveal its secrets is challenging. A new genetic 'repressilator' circuit acts like a clock that tracks how bacterial growth changes over time with single-cell precision. This tool allows scientists to noninvasively study the dynamics of the microbiome, and also unlocks the potential for complex, synthetic-biology-based diagnostics and therapeutics for the human gut.
Read moreCRISPR enzyme programmed to kill viruses in human cells
Researchers have now turned a CRISPR RNA-cutting enzyme into an antiviral that can be programmed to detect and destroy RNA-based viruses in human cells.
Read moreKey uncertainties identified for models of mosquito distribution in the US
A computational analysis has identified key regions in the United States where model-based predictions of mosquito species distribution could be improved.
Read moreImpacts of low-dose exposure to antibiotics unveiled in zebrafish gut
An antibiotic commonly found at low concentrations in the environment can have major impacts on gut bacteria, report researchers.
Read moreA Lego-like approach to improve nature's own ability to kill dangerous bacteria
A research team has demonstrated how it could improve upon the ability of nature's exquisitely selective collection of antimicrobial enzymes to attack bacteria in a way that's much less likely to cause bacterial resistance.
Read moreBiomedical sciences researchers isolate gut bacteria that can prevent and cure rotavirus infection
The presence of specific microbiota, or microorganisms that live in the digestive tract, can prevent and cure rotavirus infection, which is the leading cause of severe, life-threatening diarrhea in children worldwide, according to a new study.
Read moreCompound in breast milk fights harmful bacteria
A compound in human breast milk fights infections by harmful bacteria while allowing beneficial bacteria to thrive, according to researchers. Human breast milk has more than 200 times the amount of glycerol monolaurate (GML) than is found in cows' milk. Infant formula has none. Future research will determine if GML could be a beneficial additive to cow's milk and infant formula.
Read moreAntibiotic resistance in food animals nearly tripled since 2000
Researchers report that the growing appetite for animal protein in low- to middle-income countries has resulted in a smorgasbord of antibiotic consumption for livestock that has nearly tripled the occurrence of antibiotic resistance in disease-causing bacteria between 2000 and 2018. The researchers found that antibiotic resistance in livestock was most widespread in China and India, with Brazil and Kenya emerging as new hotspots.
Read moreTuberculosis: New insights into the pathogen
Researchers have gained new insights into the pathogen that causes tuberculosis. The work provides the basis for a new approach in antibiotic therapy.
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