For years, scientists thought that these powerful sedatives, which are used to treat anxiety, muscle spasms, and sleeping disorders, worked alone to calm nerves. Now, researchers show that this view of the drugs and the neural circuits they affect may have to change. In a study of mice, scientists discovered that both may need the assistance of a 'sticky' gene, named after a mythological figure, called Shisa7.
Read moreMultiple sclerosis, an autoimmune disorder, is known to be driven by 'helper' T cells, white blood cells that mount an inflammatory attack on the brain and spinal cord. A new study pinpoints the specific subgroup of helper T cells that cause MS, as well as a protein on their surface, called CXCR6, that marks them. An antibody targeting CXCR6 both prevented and reversed MS in a mouse model, the researchers report.
Read moreResearchers have identified a group of genetic variants related to the starting point of Parkinson's disease. These results, published in the journal Movement Disorders, will enable delimiting the research on new therapeutic targets, and could have implications in the diagnosis of the disease.
Read moreTreatments have been hard to pinpoint for a rare neurological disease called Charcot-Marie-Tooth, in part because so many variations of the condition exist. So far, mutations on more than 90 genes have been positively linked to the disorder; a patient needs just one of those mutations for the disease to emerge. Scientists just moved a step closer to finding a possible root cause.
Read moreIn a new study, researchers reveal that a lifelong dietary regimen of choline holds the potential to prevent Alzheimer's disease (AD).
Read moreVersions of an antibiotic drug called DON first isolated from soil bacteria more than 60 years ago have shown promising signs of extending survival in mice models of especially lethal pediatric brain tumors marked by the high expression of a cancer-causing gene known as the MYC oncogene.
Read moreResearchers describe a new use of leukemia drug, nilotinib, to treat a subtype of medulloblastoma, a deadly pediatric brain cancer.
Read moreA research team has examined the interplay between genetics, cardiovascular disease and educational attainment in a major population study. Genetic variants which had been linked to educational attainment in other studies were observed in the subjects. The researchers found that these variants also had implications for a more health-conscious lifestyle and thus a lower risk of cardiovascular disease – in some cases regardless of the level of education.
Read moreUsing a new technique to study brain development, scientists were able to trace the causes of Huntington's back to early developmental stages when the brain has only just begun to form.
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