Studying proteins moving (relatively) slowly

Proteins keep our organs functioning, regulate our cells and are the targets for medications that treat a number of diseases, including cancers and neurological diseases. Proteins need to move in order to function. But, because the technology they used to watch proteins doesn't allow it, scientists still know very little about such motions at speeds slower than a nanosecond. That changed last month.

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Scientists construct energy production unit for a synthetic cell

Scientists have constructed synthetic vesicles in which ATP, the main energy carrier in living cells, is produced. The vesicles use the ATP to maintain their volume and their ionic strength homeostasis. This metabolic network will eventually be used in the creation of synthetic cells – but it can already be used to study ATP-dependent processes.

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Programmable swarmbots make flexible biological tools

Biomedical engineers have developed a new platform to create biological drugs using specially engineered bacteria that burst and release useful proteins when they sense that their capsule is becoming too crowded.

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Genomic migration analysis shows antibiotic resistance moving from humans to animals

New results show that human-acquired antibiotic resistance genes are being transmitted to livestock, companion animals and wildlife. Researchers analyzed a global set of 901 genome sequences of the bacteria Streptococcus agalactiae (aka group B Strep) from nine different host species — humans, cows, dogs, fish, frogs, gray seals, dolphins, goats and a camel — to better understand the transmission process. Streptococcus agalactiae can cause life-threatening illnesses.

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Researchers unlock cancer-causing mechanism of E. coli toxin with synthetic biology approach

An inter-disciplinary team of researchers has unraveled how a toxin released by Escherichia coli (E. coli) – a human gut bacteria, is connected to colorectal cancer, offering new insights to the health impact of this prevalent bacteria and facilitating future research on the prevention of this third most common cancer worldwide.

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Too much of a good thing: Overactive immune cells trigger inflammation

Scientists describe a previously unknown disorder of the immune system: in a distinct subset of immune cells from patients with primary immunodeficiency, cellular respiration is significantly increased. This cellular metabolic overactivity leads to inflammation.

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