Fruit flies live longer with combination drug treatment
A triple drug combination has been used to extend the lifespan of fruit flies by 48% in a new study.
Read moreHIV and AIDS
How nasty Toxoplasma parasite damages the human eye
An international study used human retinal cells to demonstrate how the Toxoplasma parasite creates a characteristic eye lesion that can help doctors diagnose the infection.
Read morePotent antibody curbs Nipah and Hendra virus attack
A monoclonal antibody has been shown to impede the fusion machinery henipaviruses use to merge with the membrane of cells they are attempting to breach. The antibody halts the attack by blocking membrane fusion and the injection of the viral genome into the host cell. Researchers hope this discovery will pave the way toward preventing or treating Nipah or Hendra virus infections, which now have no vaccines or therapies for people. The main carriers are large bats called flying foxes.
Read moreImmune response against Toxocara roundworms helps explain disease
Neurotoxocarosis (NT) occurs in humans when larvae of the Toxocara roundworm migrate into the central nervous system. That infection is accompanied by a complex molecular signaling cascade, including changes to anti-inflammatory lipid molecules, researchers now report.
Read moreScientists tackle potential drug resistance by using new single-cell genetic method
Using a new technique that can identify genetic profiles of individual cells, researchers modeled a breast cancer tumor's potential resistance to a drug, and then identified a drug combination that reversed that resistance.
Read moreA protein essential for chikungunya virus replication identified
Chikungunya is an infectious disease caused by a mosquito-borne virus transmitted to humans. It is characterized by high fever and intense joint and muscle pain that can last for several months. The mechanisms of infection of human cells with the virus remain very poorly understood. Researchers have now identified a protein that is crucial in order for the virus to replicate within its target cells. This research opens up therapeutic avenues in the fight against chikungunya.
Read moreSwitch that kills inactive HIV isolated
Researchers have identified a switch controlling HIV reproduction in immune cells which can eliminate dormant HIV reservoirs.
Read moreLong-acting injectable multi-drug implant shows promise for HIV prevention and treatment
UNC researchers have created an injectable multi-drug delivery system that is removable, biodegradable and effective for up to a year in some cases. The author says the ability to administer multiple drugs with this implant is an important advancement in this research.
Read moreNew tool in fight against malaria
Modifying a class of molecules originally developed to treat the skin disease psoriasis could lead to a new malaria drug that is effective against malaria parasites resistant to currently available drugs.
Read moreTowards better hand hygiene for flu prevention
Rubbing hands with ethanol-based sanitizers should provide a formidable defense against infection from flu viruses, which can thrive and spread in saliva and mucus. But new findings challenge that notion — and suggest that there's room for improvement in this approach to hand hygiene.
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