Novel virus type may shed light on viral evolution

Viruses are non-living creatures, consisting of genetic material encased in a protein coat. Once the virus infects a living organism, it can replicate itself and continue on. But what happens if a virus lacks the proper tools to infect an organism? How can it propagate? Researchers have uncovered a novel virus that may help answer those questions.

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Potent antibody curbs Nipah and Hendra virus attack

A monoclonal antibody has been shown to impede the fusion machinery henipaviruses use to merge with the membrane of cells they are attempting to breach. The antibody halts the attack by blocking membrane fusion and the injection of the viral genome into the host cell. Researchers hope this discovery will pave the way toward preventing or treating Nipah or Hendra virus infections, which now have no vaccines or therapies for people. The main carriers are large bats called flying foxes.

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A protein essential for chikungunya virus replication identified

Chikungunya is an infectious disease caused by a mosquito-borne virus transmitted to humans. It is characterized by high fever and intense joint and muscle pain that can last for several months. The mechanisms of infection of human cells with the virus remain very poorly understood. Researchers have now identified a protein that is crucial in order for the virus to replicate within its target cells. This research opens up therapeutic avenues in the fight against chikungunya.

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