Vitamin D and fish oil show promise in prevention of cancer death and heart attacks

The VITamin D and OmegA-3 Trial (VITAL) is the largest and most recent to test whether vitamin D or fish oil can effectively prevent cancer or cardiovascular disease. Results to date have been mixed but show promise for some outcomes, now confirmed by updated pooled (meta) analyses.

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Thinner shells for delivering gentler therapeutic bursts

Releasing drugs that are packaged into microcapsules requires a significant amount of force, and the resulting burst can cause damage to human tissues or cause blood clots. A new technique creates lopsided microcapsule 'shells' that can burst and release their cargo at much lower pressure, making them safer for use in the body.

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US pediatric heart transplant waitlist policy change falls short of intended benefits

In March 2016, the Organ Procurement and Transplantation Network revised its criteria for prioritizing children awaiting heart transplantation in the US with the intention of reducing the number of deaths on the waitlist, but a new study suggests unintended consequences.

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Genetic variants with possible positive implications for lifestyle

A research team has examined the interplay between genetics, cardiovascular disease and educational attainment in a major population study. Genetic variants which had been linked to educational attainment in other studies were observed in the subjects. The researchers found that these variants also had implications for a more health-conscious lifestyle and thus a lower risk of cardiovascular disease – in some cases regardless of the level of education.

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New target regulating mitochondria during stress

Like an emergency response team that is called into action to save lives, stress response proteins in the heart are activated during a heart attack to help prevent cell death. As part of this process, researchers show for the first time that one of these specialized emergency responder proteins, known as MCUB, temporarily decreases harmful levels of calcium transport into mitochondria, the energy-generating batteries of cells.

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