Scientists have developed a computer method that may help improve understanding and treatment of Crohn's disease, which causes inflammation of the digestive tract. The study used artificial intelligence to examine genetic signatures of Crohn's in 111 people. The method revealed previously undiscovered genes linked to the disease, and accurately predicted whether thousands of other people had the disease.
Read moreResearchers have found that placebo controls are almost never described according to standard reporting guidelines.
Read moreIntestinal epithelial cells (IECs) are exposed to diverse types of environmental stresses such as bacteria and toxins, but the mechanisms by which epithelial cells sense stress are not well understood. New research has found that Nox-ROS-ASK1-MKK3-p38 signaling in IECs integrates various stresses to facilitate intestinal regeneration.
Read moreThe low FODMAP diet, a diet low in carbohydrates that trigger digestive symptoms like bloating and stomach pain, is a useful treatment in children and adolescents with gastrointestinal problems, new research confirms.
Read moreBecause researchers demonstrated for the first time that a strong association between obesity and chronic diarrhea is not driven by diet or physical activity, the findings could have important implications for how physicians might approach and treat symptoms of diarrhea in patients with obesity differently.
Read moreScientists appear to have solved a decades-long mystery regarding the precise biochemical pathway leading to a fatal genetic disorder in children that results in seizures, developmental regression and death, usually around age 3. Studying a mouse model with the same human illness — called Krabbe disease — the researchers also identified a possible therapeutic strategy.
Read moreChemical engineers have traced the journey of gases through the gut while further developing a non-invasive, gas-capturing capsule.
Read moreA highly gender-biased disease, lupus afflicts females some nine times more than males. Because of the disease's unpredictable turns and debilitating flares — the risks of which are elevated in postpartum women — females with the disease are often advised to avoid pregnancy altogether.
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