How fungal biofilm structure impacts lung disease

Findings from an innovative new study reveal that the way in which human fungal pathogens form colonies can significantly impact their ability to cause disease. Understanding how these colonies form could lead to new therapies that target these infections in critically ill patients.

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Salmonella causing bloodstream infections in central Africa resistant to nearly all drugs

The first extensively drug-resistant (XDR) strains of Salmonella Typhimurium, a pathogen which is responsible for millions of bloodstream infections per year in sub-Saharan Africa, have been identified in the Democratic Republic of Congo (DRC). Drug-resistance has increased in successive groups of S. Typhimurium over time. These new strains are resistant to all but one of the commonly available drugs in the DRC, with one sample showing reduced susceptibility to this final antibiotic.

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March of the multiple penguin genomes

A new article presents 19 high-coverage penguin genome sequences. Adding this to the two previously published penguin genomes, there are now genome sequences available for all living penguin species. Here, the Penguin Genome Consortium, made up of researchers from 10 countries, has produced an unparalleled amount of information that covers an entire biological order. Research from evolution, the impact of human activities impact, and environmental changes, will benefit from this work.

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Rare 10 million-year-old fossil unearths new view of human evolution

Near an old mining town in Central Europe, known for its picturesque turquoise-blue quarry water, lay Rudapithecus. For 10 million years, the fossilized ape waited in Rudabánya, Hungary, to add its story to the origins of how humans evolved. What Rudabánya yielded was a pelvis — among the most informative bones of a skeleton, but one that is rarely preserved.

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Genomic migration analysis shows antibiotic resistance moving from humans to animals

New results show that human-acquired antibiotic resistance genes are being transmitted to livestock, companion animals and wildlife. Researchers analyzed a global set of 901 genome sequences of the bacteria Streptococcus agalactiae (aka group B Strep) from nine different host species — humans, cows, dogs, fish, frogs, gray seals, dolphins, goats and a camel — to better understand the transmission process. Streptococcus agalactiae can cause life-threatening illnesses.

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