The molecules of life are twisted. But how those familiar strands in DNA's double helix manage to replicate without being tangled up has been hard to decipher. A new perspective from physicists is helping unravel the mystery.
Read moreScientists have observed changes to the gene-regulating factors during zebrafish development and discovered that modifications to 'histone H3', one of the proteins around which DNA is bound, play an important role in 'zygotic genome activation' or transition of control of zebrafish embryonic development from maternal material to the zygote.
Read moreResearchers have uncovered a chromosome-wide mechanism that keeps the gene expression of sex chromosomes in balance in our cells. The findings shed light on molecular reasons for early miscarriage and could be important for the emerging field of regenerative medicine.
Read moreNuclear abnormalities such as nuclear blebs and micronuclei have devastating consequences for the genetic material and are associated with cancer or ageing. Scientists now revealed that the epigenetic enzyme MOF is crucial for the morphological integrity of the mammalian nucleus. Moreover, the study characterized the epigenetic landscape of nuclear abnormalities and discovered a formerly unknown epigenetic mechanism that seems to protect cells from additional damage.
Read moreResearchers have developed an optical system that accurately measures the flow of extraordinarily tiny amounts of liquids — as small as 10 billionths of a liter (nanoliters) per minute.
Read moreA research team has revealed a new fundamental mechanism by which a cell can make necessary changes in its chromatin structure in response to different DNA-associated processes such as gene expression and DNA damage repair.
Read moreResearchers have developed an electronic chip that can perform high-sensitivity intracellular recording from thousands of connected neurons simultaneously. This breakthrough allowed them to map synaptic connectivity at an unprecedented level, identifying hundreds of synaptic connections.
Read morePotentially dangerous genes embedded within human DNA were once thought to be locked down by helpful DNA structures called heterochromatin. A researcher disputes that belief and hopes to change the paradigm even further.
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