Long-term study data shows DBS is effective treatment for most severe form of depression

Deep brain stimulation (DBS) of an area in the brain called the subcallosal cingulate (SCC) provides a robust antidepressant effect that is sustained over a long period of time in patients with treatment-resistant depression — the most severely depressed patients who have not responded to other treatments.

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Study pinpoints Alzheimer's plaque emergence early and deep in the brain

By scanning whole brains of Alzheimer's model mice from an early age, researchers were able to precisely trace the terrible march of amyloid plaques from deep brain structures outward along specific circuits. They also showed that plaque density in a key region in humans scales with disease stage.

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New neurodevelopmental syndrome and NKAP gene

Researchers have identified a gene mutation that causes developmental delay, intellectual disability, behavioral abnormalities and musculoskeletal problems in children. The newly diagnosed condition, called NKAP-related syndrome, arises from mutations in the NKAP gene, which plays a key role in human development.

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Pesticides likely caused 'Havana syndrome' that affected Cuba-based diplomats

The study details the nature of the injury, specifies the brain regions involved, including the blood-brain barrier and suggests a possible cause in the form of 'cholinesterase inhibitors,' with 'organophosphorus insecticides' being a likely source. Cholinesterase (ChE) is one of the key enzymes required for the proper functioning of the nervous systems of humans, invertebrates and insects.

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