Health care intervention: Treating high-need, high-cost patients

Patients with complex needs — serious mental and physical health problems and substance use disorders — flock to emergency rooms costing the health care system billions every year. A new study suggests a nontraditional approach to these patients can significantly improve their daily functioning and health outcomes.

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Scientists develop test for uncommon brain diseases

Scientists have developed an ultrasensitive new test to detect abnormal forms of the protein tau associated with uncommon types of neurodegenerative diseases called tauopathies. This advance gives them hope of using cerebrospinal fluid, or CSF — an accessible patient sample — to diagnose these and perhaps other, more common neurological diseases, such as Alzheimer's disease.

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New insights into biological underpinnings of schizophrenia

Researchers have implicated 10 new genes in the development of schizophrenia using a method called whole exome sequencing, the analysis of the portion of DNA that codes for proteins. A global consortium of schizophrenia research teams incorporated genetic data from over 125,000 people to gain deeper insights into the genetic underpinnings of schizophrenia.

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Protein misfolding as a risk marker for Alzheimer's disease

In symptom-free individuals, the detection of misfolded amyloid-beta protein in the blood indicated a considerably higher risk of Alzheimer's disease — up to 14 years before a clinical diagnosis was made. Amyloid-beta folding proved to be superior to other risk markers evaluated.

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Widely available drug reduces head injury deaths

A low cost and widely available drug could reduce deaths in traumatic brain injury patients by as much as 20%, depending on the severity of injury, according to a major study. The researchers say that tranexamic acid (TXA), a drug that prevents bleeding into the brain by inhibiting blood clot breakdown, has the potential to save hundreds of thousands of lives.

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Happy, angry or neutral expressions? Eyes react just as fast

Scientists have investigated how our eyes and brain react when we see emotionally charged or neutral faces. She combined eye-tracking and electroencephalography (EEG). The result: reflex-like eye movements are independent of the expression a face shows; our attention is drawn to them just as fast.

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