Disorders and Syndromes – PossibleThreat Articles

Schizophrenia risk gene linked to cognitive deficits in mice

October 24, 2019 0 Comments Disorders and Syndromes, Gene Therapy, Genes, Memory, Mental Health, Mental Health Research, Personalized Medicine, Schizophrenia

Researchers have discovered in mice how one of the few genes definitively linked to schizophrenia, called SETD1A, likely confers risk for the illness. Mice genetically engineered to lack a functioning version of the enzyme-coding gene showed abnormalities in working memory, mimicking those commonly seen in patients. Restoring the gene's function corrected the working memory deficit and counteracting its deficiency also repaired neuronal circuit deficits in adult mice — suggesting clues for potential treatment strategies.

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Genetic variations linked to oxygen drops during sleep

October 24, 2019 0 Comments COPD, Diseases and Conditions, Disorders and Syndromes, Insomnia, Insomnia Research, Obstructive Sleep Apnea, Sleep Disorder Research, Sleep Disorders

Researchers have identified 57 genetic variations of a gene strongly associated with declines in blood oxygen levels during sleep. Low oxygen levels during sleep are a clinical indicator of the severity of sleep apnea, a disorder that increases the risk of heart disease, dementia, and death.

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Young moms more likely to have kids with ADHD

October 24, 2019 0 Comments ADD and ADHD, Child Development, Child Psychology, Disorders and Syndromes, Infant and Preschool Learning, Mental Health, Parenting, Psychiatry

Young mothers have a greater chance of having a child with attention deficit hyperactivity disorder (ADHD) according to new research. Exploring the genetic relationship between female reproductive traits and key psychiatric disorders, it found that the genetic risk of ADHD in children was strongly associated with early maternal age at first birth, particular for women younger than 20.

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Breakthrough in understanding rare genetic skin condition

October 24, 2019 0 Comments Depression, Diseases and Conditions, Disorders and Syndromes, Multiple Sclerosis, Psoriasis, Skin Cancer, Stroke, Today's Healthcare

A breakthrough has been made in understanding a rare genetic skin disease that causes progressively enlarging skin tumors over the scalp, face and body.

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Gut instincts: Researchers discover first clues on how gut health influences brain health

October 24, 2019 0 Comments Birth Defects, Brain Injury, Brain Tumor, Brain-Computer Interfaces, Diseases and Conditions, Disorders and Syndromes, Gastrointestinal Problems, Intelligence

New cellular and molecular processes underlying communication between gut microbes and brain cells have been described for the first time.

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High-salt diet promotes cognitive impairment through the Alzheimer-linked protein tau

October 24, 2019 0 Comments Alzheimer's Research, Blood Clots, Brain Tumor, Dementia, Disorders and Syndromes, Hypertension, Intelligence, neuroscience

Investigators sought to understand the series of events that occur between salt consumption and poor cognition and concluded that lowering salt intake and maintaining healthy blood vessels in the brain may 'stave off' dementia. Accumulation of tau deposits has been implicated in the development of Alzheimer's disease in humans.

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Greater understanding of Alzheimer's disease

October 23, 2019 0 Comments Alzheimer's, Alzheimer's Research, Crohn's Disease, Dementia, Diseases and Conditions, Disorders and Syndromes, Healthy Aging, Memory

Scientists have made an important discovery in understanding the role a particular protein plays to impair memory in Alzheimer's disease, which could lead to more effective treatment in future.

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Dementia patients' adult kids diagnosed earlier than their parents

October 22, 2019 0 Comments Alzheimer's, Alzheimer's Research, Child Psychology, Dementia, Diabetes, Disorders and Syndromes, Elder Care, Healthy Aging

A new study indicates that people with dementia — whose parents also had dementia — develop symptoms an average of six years earlier than their parents.

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Novel agent flips on garbage disposal in neurons, eliminating toxic brain proteins in mice

October 22, 2019 0 Comments Alzheimer's, Brain Injury, Brain Tumor, Diseases and Conditions, Disorders and Syndromes, Nervous System, neuroscience, Pharmacology

Neuroscientists say they have developed and tested an agent that reduces the buildup of toxic proteins in animal models of both Parkinson's and Alzheimer's diseases, and improves cognitive and motor behavior.

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IQSEC1 gene mutations cause new intellectual disability syndrome

October 22, 2019 0 Comments Autism, Birth Defects, Brain-Computer Interfaces, Diseases and Conditions, Disorders and Syndromes, Genes, Human Biology, Huntington's Disease

Researchers identify gene causing intellectual disability syndrome that is common in countries where consanguineous marriages are prevalent.

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