Scientists have developed a new and more accurate method to identify the molecular signs of cancer likely to be presented to helper T cells, which stimulate and orchestrate the immune response to tumors and infectious agents.
Read moreWomen receive poorer heart attack treatment than men, even when rates of diagnosis are the same, according to new research.
Read moreA multi-institutional team has brought attention to genomic structural variation as a previously unappreciated mechanism involved in altering DNA methylation, a form of gene control, in human cancers.
Read moreA heart attack is caused by a clot that blocks the artery blood flow. Under these conditions, the affected tissues undergo a rapid necrosis. But why? Scientists discovered that the synthesis of a lipid provokes the necrosis. This lipid accumulates in the absence of oxygen and blocks cellular functions. By inhibiting its synthesis in a mouse suffering a heart attack, the biologists were able to reduce the tissue damage by 30%.
Read moreResearchers have discovered new changes in blood samples associated with Alzheimer's disease. A new international study was conducted on disease-discordant Finnish twin pairs: one sibling suffering from Alzheimer's disease and the other being cognitively healthy. The researchers utilised the latest genome-wide methods to examine the twins' blood samples for any disease-related differences in epigenetic marks which are sensitive to changes in environmental factors. These differences between the siblings were discovered in multiple different genomic regions.
Read moreNew research shows that the more a baby weighs at birth relative to its gestational age the higher the risk they will suffer from childhood food allergy or eczema, although not hay fever.
Read moreThe new method is leading to a better understanding of natural protein modifications and improved protein therapeutics.
Read moreResearchers have used adaptive optics technology to create the first undistorted microscopic images of the eye's trabecular meshwork, which could help improve treatment for glaucoma.
Read moreWithout fat, nothing works in the body: These substances serve as energy suppliers and important building blocks — including for the envelopes of living cells. Numerous diseases are related to disorders in the fat metabolism, such as obesity or cancer. Researchers are now demonstrating how the fat metabolism can be monitored down to the individual liver cell of a mouse with the greatest sensitivity.
Read moreAn international team of researchers has developed new genetic-based epilepsy risk scores which may lay the foundation for a more personalized method of epilepsy diagnosis and treatment. This analysis is the largest study of epilepsy genetics to date, as well as the largest study of epilepsy using human samples.
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