A new study reveals that commonly given hip and knee steroid intra-articular injections may be harmful in some patients with at-risk conditions or may cause complications that are not well understood.
Read moreResearchers examined whether there is an association between arthritis and social isolation, and have identified the disease's contribution to social isolation.
Read moreResearchers have developed a method for statistically predicting impacts of climate change on outbreaks of tularemia in humans. New results show that tularemia may become increasingly common in the future in high-latitude regions.
Read moreA new study points to the need for better antibody validation, and outlines a process that other labs can use to make sure the antibodies they work with function properly.
Read moreResearchers report that Acceptance and Commitment Therapy (ACT) shows significant promise for treating fear of cancer recurrence in women who have survived breast cancer. Fear that cancer may come back or progress is especially common in breast cancer survivors, with up to 70% reporting that the fear affects their daily life.
Read moreThe aim of immunotherapies is to enable the immune system once again to fight cancer on its own. Drugs known as checkpoint inhibitors are already in clinical use for this purpose. However, they are only effective in about one third of patients. Based on analysis of human tissue samples, a team has now discovered one reason why this is so: an inactive receptor in cancer cells prevents the drugs from reactivating the immune system.
Read moreWhen the adrenal gland produces too much aldosterone, this often leads to high blood pressure and kidney damage (hyperaldosteronism). It has only recently emerged that several patients harbor a mutation in the gene for the ClC-2 chloride channel. Researchers have now been able to show for the first time how the altered channels cause the disease.
Read moreRecent research has revealed increased inflammatory activity in a subgroup of patients with frontotemporal dementia (FTD). Increased inflammation was associated with parkinsonism symptoms and more rapid disease progression. In addition, the results showed that cancer is rare in FTD, whereas some autoimmune diseases may be more common among FTD patients. These findings may indicate an overactive immune system in FTD.
Read moreResearchers have discovered that a key cell type involved in liver injury and cancer consists of two cellular families with different origins and functions.
Read moreAn international team of researchers has published a new study examining a 430,000-year-old cranium of a human ancestor that was previously described as deaf, representing the oldest case of deafness in human prehistory.
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